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Title:
Drug toxicokinetics / edited by Peter G. Welling, Felix A. de la Iglesia.
Publisher:
M. Dekker,
Copyright Date:
c1993
Description:
xviii, 408 p. : ill. ; 24 cm.
Subject:
Drugs--Toxicology.
Pharmacokinetics.
Drugs--toxicity.
Pharmacokinetics.
Other Authors:
De la Iglesia, Felix A., 1939-
Welling, Peter G.
Notes:
Includes bibliographical references and index.
Contents:
(cont.) Application of toxicokinetic principles in the development of antiatherosclerotic compounds / Robert L. Susick and Thomas Woolf -- Toxicokinetics of drugs acting on the central nervous system / D. Scott Wright, Steven E. Rose and John R. MacDonald -- Toxicokinetics of antibacterial agents: preclinical perspective / Robert D. Smyth and Robert J. Smyth -- Perspective and future directions of toxicokinetics in drug development / Felix A. de la Iglesia.
Analytical method considerations for toxicokinetic studies / D. Scott Wright -- Pharmacokinetic principles: linear and nonlinear / Peter G. Welling -- Biotransformation of xenobiotics to chemically reactive metabolites / Neal Castagnoli, Jr. and Kay P. Castagnoli -- Role of toxicokinetics in dose selection for carcinogenicity studies / Mitchell N. Cayen and Hugh E. Black -- Toxicokinetic study design and integrated programs / Eva Halperin-Walega, Avraham Yacobi and Vijay K. Batra -- Role of toxicokinetics in toxicity testing / L.F. Chasseaud -- Relation between toxicity and kinetics and models of renal disease / Norberto Perico and Silvio Garattini -- Route of administration and toxicity / Lloyd A. Dethloff -- Genetic variations in humans and toxicokinetics / Bert N. La Du, Jr. -- Comparative histokinetic and xenodynamic considerations in toxicity / Michael J. Iatropoulos -- Toxicokinetics of anticancer compounds / Lloyd R. Whitfield and David G. Pegg -- Toxicokinetics of chemical carcinogens / Anthony J. Streeter.
Series:
Drug and chemical toxicology ; 9
ISBN:
9780824790196 (alk. paper)
0824790197 (alk. paper)
OCLC:
(OCoLC)27813419
(OCoLC)27816833
LCCN:
93016817
Locations:
USUX851 -- Iowa State University - Parks Library (Ames)

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