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Title:
The Search for antiviral drugs : case histories from concept to clinic / Julian Adams, Vincent J. Merluzzi, editors.
Publisher:
Birkhäuser,
Copyright Date:
c1993
Description:
xii, 240 p. : ill. ; 24 cm.
Subject:
Antiviral agents.
Nucleosides--Therapeutic use.--Therapeutic use.
HIV infections--Chemotherapy.
Antiviral agents.
Nucleosides--therapeutic use.
HIV Infections--drug therapy
Other Authors:
Adams, Julian, 1954-
Merluzzi, Vincent J., 1949-
Notes:
Includes bibliographical references and index.
Contents:
Introduction : the first effective antiviral / Herbert E. Kaufman -- Discovery and development of zidovudine as the cornerstone of therapy to control human immunodeficiency virus infection / Kathryn H. Pattishall -- Discovery of nevirapine, a nonnucleoside inhibitor of HIV-1 reverse transcriptase / Julian Adams and Vincent J. Merluzzi -- Discovery of TIBO, a new family of HIV-1-specific reverse transcriptase inhibitors / Rudi Pauwels -- Discovery and development of 2-pyridinone HIV-1 reverse transcriptase inhibitors / Mark E. Goldman -- Discovery and development of the HIV proteinase inhibitor Ro 31-8959 / Noel A. Roberts and Sally Redshaw -- A new approach to antiviral chemotherapy : intervention in viral gene expression by HIV tat antagonists / Ming-Chu Hsu and Steve Tam -- Discovery of pirodavir, a broad-spectrum inhibitor of rhinoviruses / Koen Andries -- sICAM-1 as a receptor antagonist for rhinoviruses : a model system of adhesion molecules as cell receptors for viruses / Steven D. Marlin.
(Cont.) Inactivation of herpes simplex virus ribonucleotide reductase by subunit association inhibitors : a potential antiviral strategy / Michel Liuzzi and Robert Déziel.
ISBN:
9783764336066 (Berlin : acid-free paper)
3764336064 (Berlin : acid-free paper)
9780817636067 (Boston : acid-free paper)
0817636064 (Boston : acid-free paper)
OCLC:
(OCoLC)27683878
LCCN:
93016405
Locations:
USUX851 -- Iowa State University - Parks Library (Ames)
UNUX074 -- University of Northern Iowa - Rod Library (Cedar Falls)
UWAX953 -- Waldorf University - Luise V. Hanson Library (Forest City)

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