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02651pam a2200349 a 4500 001 77C28EF82ACF11DE8CCE1205A8D7520A 005 200904161642.0 008 930225s1993 nyua b 001 0 eng c 010 $a 93016817 020 $a 9780824790196 (alk. paper) 020 $a 0824790197 (alk. paper) 035 $a (OCoLC)27813419 035 $a (OCoLC)27816833 040 $a DNLM/DLC $c DLC $d SILO $d UIU $d NOH $d NLM $d IWA $d SILO 050 00 $a RA1238 $b .D8 1993 245 0 $a Drug toxicokinetics / $c edited by Peter G. Welling, Felix A. de la Iglesia. 260 $a New York : $b M. Dekker, $c c1993. 300 $a xviii, 408 p. : $b ill. ; $c 24 cm. 440 0 $a Drug and chemical toxicology ; $v 9 504 $a Includes bibliographical references and index. 505 0 $a (cont.) Application of toxicokinetic principles in the development of antiatherosclerotic compounds / Robert L. Susick and Thomas Woolf -- Toxicokinetics of drugs acting on the central nervous system / D. Scott Wright, Steven E. Rose and John R. MacDonald -- Toxicokinetics of antibacterial agents: preclinical perspective / Robert D. Smyth and Robert J. Smyth -- Perspective and future directions of toxicokinetics in drug development / Felix A. de la Iglesia. 505 0 $a Analytical method considerations for toxicokinetic studies / D. Scott Wright -- Pharmacokinetic principles: linear and nonlinear / Peter G. Welling -- Biotransformation of xenobiotics to chemically reactive metabolites / Neal Castagnoli, Jr. and Kay P. Castagnoli -- Role of toxicokinetics in dose selection for carcinogenicity studies / Mitchell N. Cayen and Hugh E. Black -- Toxicokinetic study design and integrated programs / Eva Halperin-Walega, Avraham Yacobi and Vijay K. Batra -- Role of toxicokinetics in toxicity testing / L.F. Chasseaud -- Relation between toxicity and kinetics and models of renal disease / Norberto Perico and Silvio Garattini -- Route of administration and toxicity / Lloyd A. Dethloff -- Genetic variations in humans and toxicokinetics / Bert N. La Du, Jr. -- Comparative histokinetic and xenodynamic considerations in toxicity / Michael J. Iatropoulos -- Toxicokinetics of anticancer compounds / Lloyd R. Whitfield and David G. Pegg -- Toxicokinetics of chemical carcinogens / Anthony J. Streeter. 650 0 $a Drugs $x Toxicology. 650 0 $a Pharmacokinetics. 650 2 $a Drugs $x toxicity. 650 2 $a Pharmacokinetics. 700 10 $a De la Iglesia, Felix A., $d 1939- 700 10 $a Welling, Peter G. 939 $a 689792 941 $a 1 952 $l USUX851 $d 20160813041905.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=77C28EF82ACF11DE8CCE1205A8D7520AInitiate Another SILO Locator Search