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04015aam a2200457 i 4500 001 7115D266F5D411E7B33F7C0497128E48 003 SILO 005 20180110010212 008 150822s2016 sz a b 001 0 eng 010 $a 2015959573 020 $a 9783319242231 020 $a 3319242237 020 $a 3319242210 020 $a 9783319242217 035 $a (OCoLC)916592053 040 $a NLM $b eng $e rda $c NLM $d YDXCP $d BTCTA $d OCLCF $d SUC $d MMU $d UtOrBLW $d SILO 042 $a pcc 050 4 $a RC280.L8 $b L868 2016 060 00 $a W1 AD559 v.893 2016 060 10 $a WF 658 245 00 $a Lung cancer and personalized medicine. $p Current knowledge and therapies / $c Aamir Ahmad, Shirish Gadgeel, editors. 246 1 $a Current knowledge and therapies 264 1 $a Cham : $b Springer, $c [2016] 300 $a xiii, 228 pages : $b illustrations (some color). 490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v 893 504 $a Includes bibliographical references and index. 505 0 $a Lung cancer statistics / Lindsey A. Torre, Rebecca L. Siegel, and Ahmedin Jemal -- Epidemiology of lung cancer / Ann G. Schwartz and Michele L. Cote -- Lung cancer in never smokers / Gabriel Alberto Rivera and Heather Wakelee -- Immune therapy / Lysanne Lievense, Joachim Aerts, and Joost Hegmans -- Anti-angiogenesis in personalized therapy of lung cancer / Peter M. Ellis -- Target therapy in lung cancer / Stefano Cafarotti, Filippo Lococo, Patrizia Froesh, Francesco Zappa, and Dutly AndreÌ -- Mechanisms of resistance to EGFR tyrosine kinase inhibitors and therapeutic approaches: an update / Aarif Ahsan -- KRAS-Mutant lung cancers in the era of targeted therapy / Jarushka Naidoo and Alexander Drilon -- Anaplastic Lymphoma Kinase (ALK) signaling in lung cancer / Sai-Hong Ignatius Ou and Keisuke Shirai -- Chemotherapy resistance in lung cancer / Eric S. Kim -- Current state of metal-based drugs for the efficient therapy of lung cancers and lung metastases / Bernhard Biersack and Rainer Schobert. 520 $a "This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer--statistics and epidemiology of lung cancer--along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer--immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies"--Back cover. 650 12 $a Lung Neoplasms $x therapy. $2 [MeSH] $0 https://id.nlm.nih.gov/mesh/D008175Q000628 650 22 $a Precision Medicine. $2 [MeSH] $0 https://id.nlm.nih.gov/mesh/D057285 650 0 $a Lungs $x Treatment. $x Treatment. $0 http://id.loc.gov/authorities/subjects/sh2010009702 650 0 $a Personalized medicine. $0 http://id.loc.gov/authorities/subjects/sh2013003324 650 7 $a Lungs $x Treatment. $x Treatment. $2 fast $0 (OCoLC)fst01003773 650 7 $a Personalized medicine. $2 fast $0 (OCoLC)fst01910010 700 1 $a Ahmad, Aamir, $e editor. $0 http://id.loc.gov/authorities/names/nb2013004279 700 1 $a Gadgeel, Shirish, $e editor. $0 http://id.loc.gov/authorities/names/nb2016001088 776 08 $i Online version: $t Lung cancer and personalized medicine. $d Cham : Springer, [2015] $z 9783319242231 $w (OCoLC)932289183 830 0 $a Advances in experimental medicine and biology ; $v 893. $x 0065-2598 $0 http://id.loc.gov/authorities/names/n42001229 941 $a 1 952 $l OVUX522 $d 20231219011507.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=7115D266F5D411E7B33F7C0497128E48Initiate Another SILO Locator Search