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02438pam a22003494a 4500 001 137C20E42B0611DE80C1F007A8D7520A 005 20220322010427 008 031202s2004 dcua b 000 0 eng 010 $a 2003026323 020 $a 9780309090636 (pbk.) 020 $a 0309090636 (pbk.) 035 $a (OCoLC)53840363 040 $a DNLM/DLC $c DLC $d SILO $d NLM $d EYE $d IWA $d SILO 050 00 $a RA776.75 T45 2004 245 0 $a Testosterone and aging : $b clinical research directions / $c Committee on Assessing the Need for Clinical Trials of Testosterone Replacement Therapy, Board on Health Sciences Policy ; Catharyn T. Liverman and Dan G. Blazer, editors. 260 $a Washington, DC : $b National Academies Press, $c c2004. 300 $a xvii, 219 p. : $b ill. ; $c 23 cm. 504 $a Includes bibliographical references and index. 505 0 $a INTRODUCTION -- Scope of this Report -- Aging and Hormonal Changes -- Testosterone, Human Development, and Health -- Measuring Testosterone Levels -- Testosterone Therapy -- Growing Use of Testosterone Therapy -- Clinical Trials -- TESTOSTERONE AND HEALTH OUTCOMES -- Changes in Endogenous Testosterone Levels with Aging -- Literature Review -- Bone -- Body Composition and Strength -- Physical Function -- Cognitive Function -- Mood and Depression -- Sexual Function -- Health-Related Quality of Life -- Cardiovascular and Hematologic Outcomes -- Prostate Outcomes -- Other Health Outcomes -- Multiple Outcomes -- FUTURE RESEARCH DIRECTIONS -- Strategy for Future Clinical Trials in Older Men -- Recommendations -- Initial Efficacy Trials in Older Men -- Protection of Research Participants: Safety and Ethical Issues -- Additional Areas of Research -- Need for Efficacy Studies in Older Men -- Clinical Studies in Middle-Aged Men. 650 0 $a Longevity. 650 0 $a Aging $x Prevention. 650 0 $a Testosterone $x Physiological effect. 700 1 $a Liverman, Catharyn T. 700 1 $a Blazer, Dan G. $q (Dan German), $d 1944- 710 2 $a National Research Council (U.S.). $b Committee on Assessing the Need for Clinical Trials of Testosterone Replacement Therapy. 856 41 $3 Table of contents $u http://www.loc.gov/catdir/toc/ecip0411/2003026323.html 939 $a 5061818 941 $a 2 952 $l OVUX522 $d 20180118020543.0 952 $l USUX851 $d 20160820065939.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=137C20E42B0611DE80C1F007A8D7520A 994 $a 02 $b IWAInitiate Another SILO Locator Search