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Author:
Holt, Nathalia, 1980- author.
Title:
Cured : the people who defeated HIV / Nathalia Holt.
Publisher:
PlumePublished by the Penguin Group,
Copyright Date:
2015
Description:
xxi, 313 pages : illustrations ; 21 cm
Subject:
HIV infections--Treatment--Berlin.--Berlin.
Gene therapy--Berlin--Berlin--History.
HIV Infections--therapy--Germany.
Anti-HIV Agents--history--Germany.
Anti-HIV Agents--therapeutic use--Germany.
Genetic Therapy--history--Germany.
History, 20th Century--Germany.
History, 21st Century--Germany.
Hydroxyurea--history--Germany.
Hydroxyurea--therapeutic use--Germany.
Treatment Outcome--Germany.
Gene therapy.
HIV infections--Treatment.
Germany--Berlin.
History.
Notes:
First published in the United States of America by Dutton, 2014. Includes bibliographical references and index.
Contents:
A doctor, two patients, and some tests. The good doctor in denial ; A visit with the family doctor ; Death sentence? -- The disease, a drug, and its industry. Viral Trojan horse ; A weapon from the war on cancer ; The days of acting up ; Recognizing a global pandemic ; From the one percent ; But, Doctor, I don't feel sick ; The Delta 32 Mutation ; Calling all elite controllers ; Treatment in hiding -- Treating the Berlin patients. The second diagnosis ; The compassionate use exemption ; Three deadly diseases move in ; The comfort of family and strangers ; Timing ; Transplanting ; "Perhaps we have eradicated HIV" ; An unexciting recovery -- The cure. Trials ; Proof of principle ; The good doctor in court ; Not even surprising ; The promise kept ; A child cured-- so what? ; Zinc finger snap ; The abused, the respected, the relentless.
Summary:
A young molecular biologist at the forefront of HIV research, Nathalia Holt tells the historic, multilayered, and compassionate story of two patients--each known in medical literature as the Berlin Patient--and their young research-minded doctors. The backdrop is nothing less than a revolution in cultural attitudes and medical thinking. These two patients' disparate cures came twelve years apart: the first in 1996 from an experimental cancer drug, the other in 2008 from a bone marrow transplant of cells with a particular genetic mutation. Holt connects the molecular dots of these two cases for the first time, providing insight into one of the most important medical breakthroughs of our generation.--From publisher description.
ISBN:
9780142181843 (pbk.)
0142181846
OCLC:
(OCoLC)881869810
Locations:
KSPG296 -- Burlington Public Library (Burlington)
DPPE403 -- Kendall Young Library (Webster City)

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