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Title:
Handbook of drug screening / edited by Ramakrishna Seethala, Litao Zhang.
Edition:
Second edition.
Publisher:
Informa Healthcare,
Copyright Date:
2009
Description:
xiii, 489 pages : illustrations ; 24 cm.
Subject:
Drug development--Handbooks, manuals, etc.
Drugs--Testing--Handbooks, manuals, etc.
Drug Evaluation, Preclinical--methods.
Other Authors:
Seethala, Ramakrishna, 1947- http://id.loc.gov/authorities/names/n2001001797
Zhang, Litao. http://id.loc.gov/authorities/names/n2009181246
Notes:
Includes bibliographical references and index.
Contents:
Key factors for successful high-throughput screening / John G. Houston -- Critical components in high-throughput screening : challenges and new trends / Litao Zhang, Martyn N. Banks, and John G. Houston -- Hit-to-probe-to-lead optimization strategies : a biology perspective to conquer the valley of death / Anuradha Roy ... [et al.] -- Signal detection platforms for screening in drug discovery / Ramakrishna Seethala -- Proteomic analysis in drug discovery / Haiteng Deng, Yang Xu, and Linqi Zhang -- Screening and characterization of g-protein-coupled receptor ligands for drug discovery / Ge Zhang and Mary Ellen Cvijic -- Nuclear hormone receptor screening in drug discovery / Ramakrishna Seethala and Litao Zhang -- Emerging novel high-throughput screening technologies for cell-based assays / Ilona Kariv ... [et al.] -- In vitro strategies for ion channel screening in drug discovery / Ravikumar Peri, Mark Bowlby, and John Dunlop -- Wheat from chaff : general and mechanistic triage of screening hits for enzyme targets / Mark R. Harpel -- Protein kinases and phosphatases / Pirthipal Singh -- MicroRNA strategies in drug discovery / Wishva B. Herath ... [et al.] -- Strategies for screening of biologic therapeutics / Ian Foltz and Francesca Civoli -- Cryopreserved cells in functional cell-based HTS assays / Geetha Shankar and Kirk McMillan -- High-content screening with a special emphasis on cytotoxicity and cell health measurements / Ralph J. Garippa and Ann F. Hoffman -- Effective application of drug metabolism and pharmacokinetics in drug discovery / Sharon Diamond and Swamy Yeleswaram -- Compound management for drug discovery : an overview / Moneesh Chatterjee and Martyn N. Banks -- Practical approach to quantitative high throughput screening / Wei Zheng, Ke Liu, and James Inglese -- Enabling the large-scale analysis of quantitative high-throughput screening data / Noel T. Southall ... [et al.] -- Application of nanobiotechnologies for drug discovery / K.K. Jain.
Series:
Drugs and the pharmaceutical sciences ; 196
ISBN:
1420061682
9781420061680
OCLC:
(OCoLC)317249552
LCCN:
2009012407
Locations:
OVUX522 -- University of Iowa Libraries (Iowa City)

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