The role of medicinal chemistry in drug discovery / John A. Lowe III -- Process research: how much? how soon? / Neal G. Anderson -- Aromatase inhibitors for breast cancer : exemestane (Aromasin), anastrozole (Arimidex), and letrozole (Femara) / Jie Jack Li -- Quinolone antibiotics : levofloxacin (Levaquin), moxifloxacin (Avelox), gemifloxacin (Factive), and garenoxacin (T-3811) / Chris Limberakis -- Triazole antifungals : itraconazole (Sporanox), fluconazole (Diflucan), voriconazole (Vfend), and fosfluconazole (Prodif) / Andrew S. Bell -- Non-nucleoside HIV reverse transcriptase inhibitors / Arthur Harms -- Neuraminidase inhibitors for influenza : oseltamivir phosphate (Tamiflu) and zanamivir (Relenza) / Douglas S. Johnson and Jie Jack Li -- Peroxisome proliferator-activated receptor (PPAR) agonists for type 2 diabetes / Jin Li -- Angiotensin AT1 antagonists for hypertension / Larry Yet -- Leading ACE inhibitors for hypertension / Victor J. Cee and Edward J. Olhava -- Dihydropyridine calcium channel blockers for hypertension / Daniel P. Christen -- Second-generation HMG-CoA reductase inhibitors / Jeffrey A. Pfefferkorn -- Cholesterol absorption inhibitors: ezetimibe (zetia) / Stuart B. Rosenblum -- Dual selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) for depression / Marta Piñeiro-Núñez -- GABA receptor agonists for insomnia : zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Estorra, Lunesta), and indiplon / Peter R. Guzzo -- Ligands: neurontin (Gabapentin) and lyrica (Pregabalin) / Po-Wai Yuen -- Approved treatments for attention deficit hyperactivity disorder : amphetamine (Adderall), methylphenidate (Ritalin), and atomoxetine (Straterra) / David L. Gray.
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