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Title:
Characterization of nanoparticles intended for drug delivery / edited by Scott E. McNeil.
Publisher:
Humana Press,
Copyright Date:
c2011
Description:
xii, 269 p. : ill. (some col.) ; 27 cm.
Subject:
Nanoparticles--Properties.
Pharmaceutical biotechnology.
Nanoparticles--therapeutic use--Laboratory Manuals.
Drug Delivery Systems--Laboratory Manuals.
Nanotechnology--Laboratory Manuals.
Other Authors:
McNeil, Scott E.
Notes:
Includes bibliographical references and index.
Contents:
Unique benefits of nanotechnology to drug delivery and diagnostics / Scott E. McNeil -- Challenges for nanoparticle characterization / Scott E. McNeil -- Considerations when submitting nanotherapeutics to FDA/CDER for regulatory review / Katherine Tyner and Nakissa Sadrieh -- Measuring the hydrodynamic size of nanoparticles in aqueous media using batch-mode dynamic light scattering / Vincent A. Hackley and Jeffrey D. Clogston -- Characterization of nanoparticles by matrix assisted laser desorption ionization time-of-flight mass spectrometry / Uma Ramalinga ... [et al.] -- Zeta potential measurement / Jeffrey D. Clogston and Anil K. Patri -- Size measurement of nanoparticles using atomic force microscopy / Jaroslaw Grobelny ... [et al.] -- Biological tissue and cell culture specimen preparation for TEM nanoparticle characterization / Kunio Nagashima ... [et al.] -- SEM x-ray microanalysis of nanoparticles present in tissue or cultured cell thin sections / Jiwen Zheng ... [et al.] --
Detecting and measuring free gadolinium in nanoparticles for MRI imaging / Jeffrey D. Clogston and Anil K. Patri -- Lipid component quantitation by thin layer chromatography / Jeffrey D. Clogston and Anil K. Patri -- Detection and quantitative evaluation of endotoxin contamination in nanoparticle formulations by LAL-based assays / Barry W. Neun and Marina A. Dobrovolskaia -- Analysis of microbial contamination in nanoparticle formulations / Timothy M. Potter and Marina A. Dobrovolskaia -- Gold nanoparticle quantitation via fluorescence in solution and cell culture / Parag Aggarwal and Marina A. Dobrovolskaia -- Quantitation of nanoparticles in serum matrix by capillary electrophoresis / King C. Chan, Timothy D. Veenstra, and Haleem J. Issaq -- Evaluation of cytotoxicity of nanoparticulate materials in porcine kidney cells and human hepatocarcinoma cells / Timothy M. Potter and Stephan T. Stern --
Monitoring nanoparticle-treated hepatocarcinoma cells for apoptosis / Timothy M. Potter and Stephan T. Stern -- Detecting reactive oxygen species in primary hepatocytes treated with nanoparticles / Banu Zolnik, Timothy M. Potter, and Stephan T. Stern -- Assay to detect lipid peroxidation upon exposure to nanoparticles / Timothy M. Potter, Barry W. Neun, and Stephan T. Stern -- Monitoring glutathione homeostasis in nanoparticle-treated hepatocytes / Timothy M. Potter, Barry W. Neun, and Stephan T. Stern -- Autophagy monitoring assay : qualitative analysis of MAP LC3-I to II conversion by immunoblot / Christopher B. McLeland, Jamie Rodriguez, and Stephan T. Stern -- Monitoring lysosomal activity in nanoparticle-treated cells / Barry W. Neun and Stephan T. Stern -- Method for analysis of nanoparticle hemolytic properties in vitro / Barry W. Neun and Marina A. Dobrovolskaia --
Method for in vitro analysis of nanoparticle thrombogenic properties / Barry W. Neun and Marina A. Dobrovolskaia -- Qualitative analysis of total complement activation by nanoparticles / Barry W. Neun and Marina A. Dobrovolskaia -- Method for analysis of nanoparticle effects on cellular chemotaxis / Sarah L. Skoczen, Timothy M. Potter, and Marina A. Dobrovolskaia -- In vitro analysis of nanoparticle uptake by macrophages using chemiluminescence / Sarah L. Skoczen, Timothy M. Potter, and Marina A. Dobrovolskaia.
Series:
Springer protocols
Methods in molecular biology, 1064-3745 ; 697
ISBN:
1603271988 (e-ISBN)
9781603271981 (e-ISBN)
160327197X (hbk. : alk. paper)
9781603271974 (hbk. : alk. paper)
OCLC:
(OCoLC)694899396
LCCN:
2010938916
Locations:
OVUX522 -- University of Iowa Libraries (Iowa City)

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