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03444aam a2200349 a 4500 001 275AA1A8019E11E89C78220097128E48 003 SILO 005 20180125010234 008 090323t20092009nyua bf 001 0 eng 010 $a 2009012407 020 $a 1420061682 020 $a 9781420061680 035 $a (OCoLC)317249552 040 $a DNLM/DLC $c DLC $d NLM $d C#P $d UtOrBLW $d SILO 042 $a pcc 050 00 $a RM301.25 $b .H36 2009 245 00 $a Handbook of drug screening / $c edited by Ramakrishna Seethala, Litao Zhang. 250 $a Second edition. 264 1 $a New York : $b Informa Healthcare, $c [2009] 300 $a xiii, 489 pages : $b illustrations ; $c 24 cm. 490 1 $a Drugs and the pharmaceutical sciences ; $v 196 504 $a Includes bibliographical references and index. 505 0 $a Key factors for successful high-throughput screening / John G. Houston -- Critical components in high-throughput screening : challenges and new trends / Litao Zhang, Martyn N. Banks, and John G. Houston -- Hit-to-probe-to-lead optimization strategies : a biology perspective to conquer the valley of death / Anuradha Roy ... [et al.] -- Signal detection platforms for screening in drug discovery / Ramakrishna Seethala -- Proteomic analysis in drug discovery / Haiteng Deng, Yang Xu, and Linqi Zhang -- Screening and characterization of g-protein-coupled receptor ligands for drug discovery / Ge Zhang and Mary Ellen Cvijic -- Nuclear hormone receptor screening in drug discovery / Ramakrishna Seethala and Litao Zhang -- Emerging novel high-throughput screening technologies for cell-based assays / Ilona Kariv ... [et al.] -- In vitro strategies for ion channel screening in drug discovery / Ravikumar Peri, Mark Bowlby, and John Dunlop -- Wheat from chaff : general and mechanistic triage of screening hits for enzyme targets / Mark R. Harpel -- Protein kinases and phosphatases / Pirthipal Singh -- MicroRNA strategies in drug discovery / Wishva B. Herath ... [et al.] -- Strategies for screening of biologic therapeutics / Ian Foltz and Francesca Civoli -- Cryopreserved cells in functional cell-based HTS assays / Geetha Shankar and Kirk McMillan -- High-content screening with a special emphasis on cytotoxicity and cell health measurements / Ralph J. Garippa and Ann F. Hoffman -- Effective application of drug metabolism and pharmacokinetics in drug discovery / Sharon Diamond and Swamy Yeleswaram -- Compound management for drug discovery : an overview / Moneesh Chatterjee and Martyn N. Banks -- Practical approach to quantitative high throughput screening / Wei Zheng, Ke Liu, and James Inglese -- Enabling the large-scale analysis of quantitative high-throughput screening data / Noel T. Southall ... [et al.] -- Application of nanobiotechnologies for drug discovery / K.K. Jain. 650 0 $a Drug development $v Handbooks, manuals, etc. 650 0 $a Drugs $x Testing $v Handbooks, manuals, etc. 650 12 $a Drug Evaluation, Preclinical $x methods. $2 [MeSH] $0 https://id.nlm.nih.gov/mesh/D004353Q000379 700 1 $a Seethala, Ramakrishna, $d 1947- $0 http://id.loc.gov/authorities/names/n2001001797 700 1 $a Zhang, Litao. $0 http://id.loc.gov/authorities/names/n2009181246 830 0 $a Drugs and the pharmaceutical sciences ; $v v. 196. $0 http://id.loc.gov/authorities/names/n42009973 941 $a 1 952 $l OVUX522 $d 20191126013022.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=275AA1A8019E11E89C78220097128E48Initiate Another SILO Locator Search