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05523aam a2200373 i 4500 001 FB1DC90EE96D11E8978F920F97128E48 003 SILO 005 20181116010210 008 180208t20182018nyua b 001 0deng d 010 $a 2018939547 020 $a 9781493978243 020 $a 1493978241 035 $a (OCoLC)1022085172 040 $a YDX $b eng $e rda $c YDX $d GZM $d OCLCO $d OCLCF $d NUI $d SILO 245 00 $a Huntington's disease / $c edited by Sophie V. Precious, Anne E. Rosser, and Stephen B. Dunnett. 264 1 $a New York, NY : $b Humana Press : $c [2018] 300 $a xv, 642 pages : $b illustrations (some color) ; $c 27 cm. 490 1 $a Methods in molecular biology, $x 1064-3745 ; $v volume 1780 490 1 $a Springer protocols, $x 1949-2448 504 $a Includes bibliographical references and index. 505 00 $t Quality assessment and production of human cells for clinical use / $r Lindsay Fraser, Kevin Bruce, John M. Campbell, and Paul A. De Sousa. $t Assessing autophagic activity and aggregate formation of mutant huntingtin in mammalian cells / $r Eleanna Stamatakou, Ye Zhu, and David C. Rubinsztein -- $t Filter retardation assay facilitates the detection and quantification of heat-stable, amyloidogenic mutant huntingtin aggregates in complex biosamples / $r Anne Ast, Franziska Schindler, Alexander Buntru, Sigrid Schnoegl, and Erich E. Wanker -- $t Cellular models : HD patient-derived pluripotent stem cells / $r Charlene Geater, Sarah Hernandez, Leslie Thompson, and Virginia B. Mattis -- $t Nonmammalian models of Huntington's Disease / $r Anjalika Chongtham, Brett Barbaro, Tomas Filip, Adeela Syed, Weijian Huang, Marianne R. Smith, and J. Lawrence Marsh -- $t Mouse models of Huntington's Disease / $r Pamela P. Farshim and Gillian P. Bates -- $t Motor assessment in Huntington's Disease mice / $r Stephen B. Dunnett and Simon P. Brooks -- $t Automated operant assessments of Huntington's Disease mouse models / $r Emma Yhnell and Andreas Heuer -- $t Neurophysiological assessment of Huntington's Disease model mice / $r Elissa J. Donzis, Sandra M. Holley, Carlos Cepeda, and Michael S. Levine -- $t Murine models of Huntington's Disease for evaluating therapeutics / $r Natalia Kosior and Blair R. Leavitt -- $t Generating excitotoxic lesion models of Huntington's Disease / $r Mariah J. Lelos and Stephen B. Dunnett -- $t Large-brained animal models of Huntington's Disease : sheep / $r A. Jennifer Morton -- $t Minipigs as a large-brained animal model for Huntington's Disease : from behavior and imaging to gene therapy / $r Ralf Reilmann and Verena Schuldenzucker -- $t Nonhuman primate models of Huntington's Disease and their application in translational research / $r Romina Aron Badin -- $t In vivo multidimensional brain imaging in Huntington's Disease animal models / $r Julien Flament, Philippe Hantraye, and Julien Valette -- $t Magnetic resonance imaging in Huntington's Disease / $r Sarah Gregory, Rachael I. Scahill, Geraint Rees, and Sarah Tabrizi -- $t Biofluid biomarkers in Huntington's Disease / $r Filipe B. Rodrigues, Lauren M. Byrne, and Edward J. Wild -- $t Assessing and modulating kynurenine pathway dynamics in Huntington's Disease : focus on kynurenine 3-monooxygenase / $r Korrapati V. Sathyasaikumar, Carlo Breda, Robert Schwarcz, and Flaviano Giorgini -- $t Assessing mitochondrial function in in vitro and ex vivo models of Huntington's Disease / $r I. LuiÌsa Ferreira, Catarina Carmo, Luana Naia, Sandra I. Mota, and A. Cristina Rego -- $t Using genomic data to find disease-modifying loci in Huntington's Disease (HD) / $r Peter Holmans and Tim Stone -- $t CRISPR/Cas9-mediated genome editing for Huntington's Disease / $r Gabriel Vachey and Nicole DeÌglon -- $t Methods for assessing DNA repair and repeat expansion in Huntington's Disease / $r Thomas Massey, Branduff McAllister, and Lesley Jones -- $t Translating antisense technology into a treatment for Huntington's Disease / $r Roger M. Lane, Anne Smith, Tiffany Baumann, Marc Gleichmann, Dan Norris, C. Frank Bennett, and Holly Kordasiewicz -- $t Disease modification through trophic factor delivery / $r Mari Savolainen, Dwaine Emerich, and Jeffrey H. Kordower -- $t Methods to quantify cell signaling and GPCR receptor ligand bias : characterization of drugs that target the endocannabinoid receptors in Huntington's Disease / $r Amina M. Bagher, Robert B. Laprairie, Melanie E. M. Kelly, and Eileen M. Denovan-Wright -- $t Dissection and preparation of human primary fetal ganglionic eminence tissue for research and clinical applications / $r Victoria H. Roberton, Anne E. Rosser, Anne-Marie McGorrian, and Sophie V. Precious -- $t Robust induction of DARPP32-expressing GABAergic striatal neurons from human pluripotent stem cells / $r Marija Fjodorova and Meng Li -- $t Quality assessment and production of human cells for clinical use / $r Lindsay Fraser, Kevin Bruce, John M. Campbell, and Paul A. De Sousa. 650 0 $a Huntington's disease $v Laboratory manuals. 650 7 $a Huntington's disease. $2 fast $0 (OCoLC)fst00964257 655 7 $a Laboratory manuals. $2 lcgft 655 7 $a Laboratory manuals. $2 fast $0 (OCoLC)fst01920776 700 1 $a Precious, Sophie V., $e editor. 700 1 $a Rosser, Anne E., $e editor. 700 1 $a Dunnett, S. B. $q (Stephen B.), $e editor. 773 18 $w 990001282000202771 $g no:31858069599102 830 0 $a Springer protocols (Series), $x 1949-2448 830 0 $a Methods in molecular biology (Clifton, N.J.) ; $v v. 1780. $x 1064-3745 941 $a 1 952 $l OVUX522 $d 20190212014625.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=FB1DC90EE96D11E8978F920F97128E48Initiate Another SILO Locator Search