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Title:

Statistical human genetics : methods and protocols / edited by Robert C. Elston.

Edition:

Second edition.

Publisher:

Humana Press,

Copyright Date:

2017

Description:

xii, 689 pages : illustrations (some color) ; 27 cm.

Subject:

Human genetics--Statistical methods.
Human genetics--Statistical methods.
Laboratory manuals.

Other Authors:

Elston, Robert C., 1932- editor.

Notes:

Includes bibliographical references and index.

Contents:

Processing and analyzing human microbiome data / Xuan Zhu, Jian Wang, Cielito Reyes-Gibby, and Sanjay Shete. Identification of genotype errors / Jeffery O'Connell and Yin Yao -- Detecting pedigree relationship errors / Lei Sun -- Identifying cryptic relationships / Lei Sun, Apostolos Dimitromanolakis, and Wei-Min Chen -- Estimating allele frequencies / Indra Adrianto and Courtney Montgomery -- Testing departure from hardy-weinberg proportions / Jian Wang and Sanjay Shete -- Estimating disequilibrium coefficients / Maren Vens and Andreas Ziegler -- Detecting familial aggregation / Adam C. Naj and Terri H. Beaty -- Estimating heritability from twin studies / Katrina L. Grasby, Karin J.H. Verweij, Miriam A. Mosing, Brendan P. Zietsch, and Sarah E. Medland -- Estimating heritability from nuclear family and pedigree data / Murielle Bochud -- Correcting for ascertainment / Warren Ewens and Robert C. Elston -- Segregation analysis using the unified model / Xiangqing Sun -- Design considerations for genetic linkage and association studies / Jeremie Nsengimana and D. Timothy Bishop -- Model-based linkage analysis of a quantitative trait / Yeunjoo E. Song, Sunah Song, and Audrey H. Schnell -- Model-based linkage analysis of a binary trait / Rita M. Cantor -- Model-free linkage analysis of a quantitative trait / Nathan J. Morris and Catherine M. Stein -- Model-free linkage analysis of a binary trait / Wei Xu, Jin Ma, Celia M.T. Greenwood, Andrew D. Paterson, and Shelley B. Bull -- Single marker association analysis for unrelated samples / Gang Zheng, Ao Yuan, Qizhai Li, and Joseph L. Gastwirth -- Single marker family-based association analysis conditional on parental information / Ren-Hua Chung, Daniel D. Kinnamon, and Eden R. Martin -- Single marker family-based association analysis not conditional on parental information / Junghyun Namkung and Sungho Won -- Calibrating population stratification in association analysis / Huaizhen Qin and Xiaofeng Zhu -- Cross-phenotype association analysis using summary statistics from GWAS / Xiaoyin Li and Xiaofeng Zhu -- Haplotype inference / Sunah Song, Xin Li, and Jing Li -- Multi-SNP haplotype analysis methods for association analysis / Daniel O. Stram -- Analysis of ethnic mixtures / Xiaofeng Zhu and Heming Wang -- Detecting multiethnic rare variants / Weiwei Ouyang, Xiaofeng Zhu, and Huaizhen Qin -- Identifying gene interaction networks / Danica Wiredja and Gurkan Bebek -- Structural equation modeling / Catherine M. Stein, Nathan J. Morris, Noemi B. Hall, and Nora L. Nock -- Mendelian randomization / Sandeep Grover, Fabiola Del Greco M., Catherine M. Stein, and Andreas Ziegler -- Preprocessing and quality control for whole-genome sequences from the illumina HiSeq X platform / Marvin N. Wright, Damian Gola, and Andreas Ziegler -- Processing and analyzing human microbiome data / Xuan Zhu, Jian Wang, Cielito Reyes-Gibby, and Sanjay Shete.

Summary:

The aim of this volume is to make computer programs for analyzing human genetic data more easily accessible to the beginner.

Series:

Methods in molecular biology, 1064-3745 ; 1666
Springer protocols, 1949-2448

ISBN:

9781493972739
1493972731

OCLC:

(OCoLC)988276121

LCCN:

2017951222

Locations:

OVUX522 -- University of Iowa Libraries (Iowa City)