Studies on steroid receptor coactivators in prostate cancer / Zoran Culig and Frédéric R. Santer. Methods to study angiogenesis in a mouse model of prostate cancer / Ana-Rita Pedrosa, Alexandre Trindade, and António Duarte -- Methodologies applied to establish cell cultures in prostate cancer / Anne T. Collins -- Protocols for migration and invasion studies in prostate cancer / Arjanneke F. van de Merbel, Geertje van der Horst, Jeroen T. Buijs, and Gabri van der Pluijm -- Transplantable animal studies and whole-body optical imaging in prostate carcinoma / Geertje van der Horst, Maaike van der Mark, Henry Cheung, and Gabri van der Pluijm -- Protocols for tissue microarrays in prostate cancer studies / Tatjana Vlajnic, Serenella Eppenberger-Castori, and Lukas Bubendorf -- Functional studies on steroid receptors / Simon Schlanger and Hannelore V. Heemers-- Protocols for studies on TMPRSS2/ERG in prostate cancer / Hubert Pakula, Douglas E. Linn, Daniel R. Schmidt, Marit Van Gorsel, Matthew G. Vander Heiden, and Zhe Li -- Protocols for the study of taxanes chemosensitivity in prostate cancer / M. Luz Flores and Carmen Sáez -- Method for prostate and breast cancer cell spheroid cultures using gelatin methacryloyl-based hydrogels / Christoph Meinert, Christina Theodoropoulos, Travis J. Klein, Dietmar W. Hutmacher, and Daniela Loessner -- Protocols for studies on genetically engineered mouse models in prostate cancer / Chris W. D. Armstrong, Oksana Lyubomska, Melissa J. LaBonte, and David J. J. Waugh -- Protocols for studies on stromal cells in prostate cancer / Damien A. Leach and Grant Buchanan -- Techniques for evaluation of AR transcriptional output and recruitment to DNA / Manqi Zhang, William C. Krause, and Irina U. Agoulnik -- NMR-based prostate cancer metabolomics / Leslie R. Euceda, Maria K. Andersen, May-Britt Tessem, Siver A. Moestue, Maria T. Grinde, and Tone F. Bathen -- Studies on steroid receptor coactivators in prostate cancer / Zoran Culig and Frédéric R. Santer.
Summary:
This volume presents methods and protocols on modern analysis of steroid receptor and prostate cancer function. Chapters detail androgen, androgen receptor action, anti-androgen enzalutamide, in vitro and in vivo models, imaging, gene fusions, and help facilitate studies with novel drugs including anti-androgens and chemotherapeutics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Prostate Cancer: Methods and Protocols aims to provide easily reproducible techniques.
Series:
Methods in molecular biology, 1064-3745 ; 1786 Springer protocols, 1949-2448
This resource is supported by the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act as administered by State Library of Iowa.