Metal ions and infectious diseases: an overview from the clinic / Peggy L. Carver -- Sodium and potassium in health and disease / Hana R. Pohl, John Wheeler, and H. Edward Murray -- Magnesium in health and disease / Andrea M. P. Romani -- Calcium in health and disease / Marisa Brini, Denis Ottolini, Tito Calì€, and Ernesto Carafoli -- Vanadium: its role for humans / Dieter Rehder -- Chromium: is it essential, pharmacologically relevant or toxic? / John B. Vincent -- Manganese in health and disease / Daiana Silva Avila, Robson Luiz Puntel, and Michael Aschner -- Iron: effect of overload and deficiency / Robert C. Hider and Xiaole Kong -- Cobalt: its role in health and disease / Kazuhiro Yamada -- Nickel and Human Health / Barbara Zambelli and Stefano Ciurli -- Copper: effects of deficiency and overload / Ivo Scheiber, Ralf Dringen, and Julian F. B. Mercer -- Zinc and human disease / Wolfgang Maret -- Molybdenum in human health and disease / Guenter Schwarz and Abdel A. Belaidi -- Silicon: the health benefits of a metalloid / Keith R. Martin -- Arsenic: can this toxic metalloid sustain life? / Dean E. Wilcox -- Selenium: role of the essential metalloid in health / Suguru Kurokawa and Marla J. Berry.
Summary:
"MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3 metalloids: The bulk metals sodium, potassium, magnesium, and calcium, plus the trace elements manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of which are essential for life. Also covered are chromium, vanadium, nickel, silicon, and arsenic, which have been proposed as being essential for humans in the 2nd half of the last century. However, if at all, they are needed only in ultra-trace amounts, and because of their prevalence in the environment, it has been difficult to prove whether or not they are required. In any case, all these elements are toxic in higher concentrations and therefore, transport and cellular concentrations of at least the essential ones, are tightly controlled; hence, their homeostasis and role for life, including deficiency or overload, and their links to illnesses, including cancer and neurological disorders, are thoroughly discussed. Indeed, it is an old wisdom that metals are indispensable for life. Therefore, volume 13 provides in an authoritative and timely manner in 16 stimulating chapters, written by 29 internationally recognized experts from 7 nations, and supported by more than 2750 references, and over 20 tables and 80 illustrations, many in color, a most up-to-date view on the vibrant research area of the Interrelations between essential metal ions and human diseases"--Publisher's description.
Series:
Metal ions in life sciences, 1559-0836 ; volume 13
This resource is supported by the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act as administered by State Library of Iowa.