474 records matched your query
03646aam a2200361Ii 4500 001 EB4FBC40939111E7A673E95E97128E48 003 SILO 005 20170907010029 008 170605s2017 dcua 000 0 eng d 020 $a 0309457769 020 $a 9780309457767 035 $a (OCoLC)989056837 040 $a BTCTA $b eng $e rda $c BTCTA $d OCLCQ $d YDX $d NRC $d OCLCO $d SILO 050 4 $a RC140.5 I58 2017 110 2 $a National Academies of Sciences, Engineering, and Medicine (U.S.). $b Committee on Clinical Trials During the 2014-2015 Ebola Outbreak, $e author. 245 00 $a Integrating clinical research into epidemic response : $b the Ebola experience / $c Gerald Keusch, Keith McAdam, Patricia A. Cuff, Michelle Mancher, and Emily R. Busta, editors ; Committee on Clinical Trials During the 2014--2015 Ebola Outbreak, Board on Global Health, Board on Health Sciences Policy, Health and Medicine Division, a report of the National Academies of Sciences, Engineering, Medicine. 264 1 $a Wasington, DC : $b National Academies Press $c 2017. 300 $a xxvi 316 pages : $b color illustrations ; $c 23 cm. 504 $a Includes bibliographical references. 505 0 $a Introduction -- Conducting clinical research during an epidemic -- Assessment of therapeutic trials -- Assessment of vaccine trials -- Strengthening capacity for response and research -- Engaging communities in research and response -- Facilitating international coordination and collaboration -- Appendices. Study approach and methods -- Clinical trial designs -- Ethical principles for research with human subjects -- Biographical sketches of committee members and staff. 520 $a "The 2014-2015 Ebola epidemic in western Africa was the longest and most deadly Ebola epidemic in history, resulting in 28,616 cases and 11,310 deaths in Guinea, Liberia, and Sierra Leone. The Ebola virus has been known since 1976, when two separate outbreaks were identified in the Democratic Republic of Congo (then Zaire) and South Sudan (then Sudan). However, because all Ebola outbreaks prior to that in West Africa in 2014-2015 were relatively isolated and of short duration, little was known about how to best manage patients to improve survival, and there were no approved therapeutics or vaccines. When the World Heath Organization declared the 2014-2015 epidemic a public health emergency of international concern in August 2014, several teams began conducting formal clinical trials in the Ebola affected countries during the outbreak. Integrating Clinical Research into Epidemic Response: The Ebola Experience assesses the value of the clinical trials held during the 2014-2015 epidemic and makes recommendations about how the conduct of trials could be improved in the context of a future international emerging or re-emerging infectious disease events"--Publisher's description. 650 0 $a Ebola virus disease $x Treatment $z Africa, West. 650 0 $a Clinical trials $z Africa, West. 700 1 $a Keusch, Gerald, $e editor. 700 1 $a McAdam, Keith P. W. J., $e editor. 700 1 $a Cuff, Patricia A., $e editor. 700 1 $a Mancher, Michelle, $e editor. 700 1 $a Busta, Emily R. $e editor. 776 08 $i Online version : $a National Academies of Sciences, Engineering, and Medicine (U.S.). Committee on Clinical Trials During the 2014--2015 Ebola Outbreak. $t Integrating clinical research into epidemic response. $d Washington, D.C. : National Academies Press, [2017] $z 9780309457774 $w (OCoLC)992788402 941 $a 1 952 $l USUX851 $d 20180502011746.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=EB4FBC40939111E7A673E95E97128E48 994 $a C0 $b IWAInitiate Another SILO Locator Search