Inborn errors of immunity. History of immunology -- The insect immune system -- Evolution of the vertebrate and lower deuterostome immune system -- The plant immune system -- Immunometabolism -- Regulated cell death in the immune system -- Lymphoid tissues and organs -- Type I cytokines, inteferons, and their receptors -- Tumor necrosis factor superfamily of cytokines and receptors -- Chemokines and chemokine receptors -- Pattern recognition receptors and the IL-1 family -- The complement system -- Neutrophils -- Macrophages -- Mast cells and basophils -- Eosinophils -- The biology of natural killer cells and innate lymphoid cells -- The major histocompatibility complex -- Classical antigen processing and presentation -- Immunogloblins: structure and function -- Immunogobulins: molecular genetics -- T cell antigen receptors and antigen recognition -- Antigen receptor signaling -- B cell development in mice -- B cell responses -- T cell development in the thymus -- CD4+ helper T cells: differentiation, flexibility, and heterogeneity -- Regulatory T cells -- CD8+ T cell memory -- Cytotoxic effector functions -- Immunologic tolerance -- Fc receptors and their role in immune regulation and inflammation -- Dendritic cells -- Gamma delta T cells -- CD1-restricted T cells -- Mucosal-associated invariant T cells and other MR1-reactive T cells -- The mucosal immune system -- Introduction to neuroimmunology -- Vaccines -- Maternal-fetal immunology -- Response to parasites -- Immune responses to bacteria -- Response to viruses -- Immunology of HIV infection -- Autoimmunity and autoimmune diseases -- Immunologic mechanisms of allergic disorders -- Transplantation immunology -- Cancer immunology and immunotherapy -- Inborn errors of immunity.
Summary:
"Defining the field of immunology for 40 years, Paul's Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It's an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role." Back cover.
This resource is supported by the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act as administered by State Library of Iowa.