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Author:
Herrup, Karl, author.
Title:
How not to study a disease : the story of Alzheimer's / Karl Herrup.
Publisher:
The MIT Press,
Copyright Date:
2021
Description:
x, 257 pages : illustrations ; 24 cm
Subject:
Alzheimer's disease.
Alzheimer's disease--History.--History.
Biological models.
Alzheimer Disease
Models, Biological
Biological models.
Alzheimer's disease.
Alzheimer's disease--Research.
History.
Notes:
Includes bibliographical references (pages [249]-254) and index.
Contents:
14. Final Thoughts. 1. A Layperson's History Of Alzheimer's Disease -- 2. A Physician's History Of Alzheimer's Disease -- 3. A Scientist's History Of Alzheimer's Disease -- 4. Mystery Solved! How Four Discoveries Transformed An Entire Field -- II. What Happened To Our Cure? -- 5. Building A Model Of Alzheimer's Disease -- III. Double-Edged Swords -- 6. Federal Support Of Basic Biomedical Research -- 7. The Pharmaceutical And Biotech Industry -- 8. Testing Our Models: Breaking Bad -- 9. What Is Alzheimer's Disease? -- IV. Where Shall We Go From Here? -- 10. A Layperson's Guide To The Biology Of Aging -- 11. Building A New Model Of Alzheimer's Disease -- 12. Rebalancing Our Research Portfolio -- 13. Rebalancing Our Institutions -- 14. Final Thoughts.
Summary:
"For decades, some of our best and brightest medical scientists have dedicated themselves to finding a cure for Alzheimer's disease. What happened? Where is the cure? The biggest breakthroughs occurred twenty-five years ago, with little progress since. In How Not to Study a Disease, neurobiologist Karl Herrup explains why the Alzheimer's discoveries of the 1990s didn't bear fruit and maps a direction for future research. Herrup describes the research, explains what's taking so long, and offers an approach for research in the future"--Book jacket flap.
"A trade book on Alzheimer's disease - its human face, some insights into its biology, the discoveries that seemed a path to prevention if not cure, 25 years without progress, and a new path forward"-- Provided by publisher.
ISBN:
0262546019
9780262546010
0262045907
9780262045902
OCLC:
(OCoLC)1195820240
LCCN:
2020040776
Locations:
OVUX522 -- University of Iowa Libraries (Iowa City)

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