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Title:
Essential concepts in toxicogenomics / edited by Donna L. Mendrick, William B. Mattes.
Publisher:
Humana,
Copyright Date:
c2008
Description:
xi, 277 p., 8 p. of plates : ill. (some col.) ; 25 cm.
Subject:
Toxicogenetics.
Genetic toxicology.
Genomics.
Toxicologie génétique.
Génomique.
Other Authors:
Mendrick, Donna L.
Mattes, William B.
Notes:
Includes bibliographical references and index.
Contents:
Toxicogenomics and classical toxicology, how to improve prediction and mechanistic understanding of human toxicity / Donna L. Mendrick -- Use of traditional endpoints and gene dysregulation to understand mechanisms of toxicity / Wayne R. Buck, Jeffrey F. Waring, Eric A. Blomme -- Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications / Karol L. Thompson and Joseph Hackett -- Role of statistics in toxicogenomics / Michael Elashoff -- Predictive toxicogenomics in preclinical discovery / Scott A. Barros and Rory B. Martin -- In vivo predictive toxicogenomics / Mark W. Porter -- Bioinformatics, databasing and gene annotation / Lyle D. Burgoon and Timothy R. Zacharewski -- Microarray probe mapping and annotation in cross - species comparative toxicogenomics / John N Calley, William B Mattes, Timothy P. Ryan -- Toxicogenomics in biomarker discovery -- Marc F. DeCristofaro, Kellye K. Daniels -- From pharmacogenomics to translational biomarkers / Donna L. Mendrick -- Public consortium efforts in toxicogenomics / William B. Mattes -- Applications of toxicogenomics to nonclinical drug development / Frank D. Sistare, Joseph J. DeGeorge.
Series:
Methods in molecular biology ; 460
ISBN:
1603270485 (e-book)
9781603270489 (e-book)
1588296385 (alk. paper)
9781588296382 (alk. paper)
LCCN:
2008921701
Locations:
USUX851 -- Iowa State University - Parks Library (Ames)
OVUX522 -- University of Iowa Libraries (Iowa City)

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