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Title:
Human genome epidemiology : building the evidence for using genetic information to improve health and prevent disease / edited by Muin J. Khoury ... [et al.].
Edition:
2nd ed.
Publisher:
Oxford University Press,
Copyright Date:
2010
Description:
xxiii, 676 p. : ill. ; 25 cm.
Subject:
Genetic disorders--Epidemiology.
Medical genetics--Methodology.
Genomics.
Genetics, Medical--methods.
Genetic Diseases, Inborn--epidemiology.
Genetic Predisposition to Disease--epidemiology.
Genetic Testing.
Genome, Human.
Genomics.
Other Authors:
Khoury, Muin J.
Notes:
Includes bibliographical references and index.
Contents:
Human genome epidemiology: the road map revisited -- Principles of analysis of germline genetics -- The public health genomics enterprise -- Navigating the evolving knowledge of human genetic variation in health and disease -- The global emergence of epidemiological biobanks: opportunities and challenges -- Case-control and cohort studies in the age of genome-wide associations -- The emergence of networks in human genome epidemiology: challenges and opportunities -- Design and analysis issues in genome-wide association studies -- The challenge of assessing complex gene-environment and gene-gene interactions -- STrengthening the REporting of genetic association studies (STREGA)-an extension of the STROBE statement -- Integration of the evidence on gene-disease associations: methods of HuGE reviews -- Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases -- Colorectal cancer -- Childhood leukemias -- Bladder cancer -- Type 2 diabetes -- Osteoporosis -- Preterm birth -- Coronary heart disease -- Schizophrenia -- Mendelian randomization: the contribution of genetic epidemiology to elucidating environmentally modifiable causes of disease -- Evaluation of predictive genetic tests for common diseases: bridging epidemiological, clinical, and public health measures -- The evaluation of genomic applications in practice and prevention (EGAPP) initiative: methods of the EGAPP working group -- Rapid, evidence-based reviews of genetic tests -- Role of social and behavioral research in assessing the utility of genetic information -- Assessing the evidence for clinical utility in newborn screening -- The role of epidemiology in assessing the potential clinical impact of pharmacogenomics -- The human epigenome and cancer -- The use of family history in public health practice: the epidemiologic view -- Cytochrome P450 testing in the treatment of depression -- A rapid-ACCE review of CYP2CP and VKORC1 allele testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding -- Hereditary hemochromatosis: population screening for gene mutations.
ISBN:
0195398440 (cloth : alk. paper)
9780195398441 (cloth : alk. paper)
OCLC:
(OCoLC)320493100
LCCN:
2009018899
Locations:
USUX851 -- Iowa State University - Parks Library (Ames)

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