Part 1. Network motifs -- Transcription networks : basic concepts -- Autoregulation : a network motif -- The feed forward loop network motif -- Temporal programs and the global structure of transcription networks -- Positive feedback, bistability and memory -- How to build a biological oscillator -- Part 2. Robustness -- Kinetic proofreading and conformational proofreading -- Robust signalling by bifunctional componets -- Robustness in bacterial chemotaxis -- Fold-change detection -- Dynamical compensation and mutal resistance in tissues -- Robust spatial patterning in development -- Part 3. Optimality -- Optimal gene circuit design -- Multi-objective optimality in biology -- Modularity.
Series:
Mathematical and computational biology Chapman & Hall/CRC mathematical and computational biology series
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