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Title:
Molecular profiling : methods and protocols / edited by Virginia Espina and Lance A. Liotta.
Publisher:
Humana,
Copyright Date:
c2012
Description:
xiii, 447 p. : ill. (some col.) ; 27 cm.
Subject:
Molecular diagnosis--Laboratory manuals.
Pathology, Molecular--Laboratory manuals.
Other Authors:
Espina, Virginia.
Liotta, L. A. (Lance A.)
Notes:
Includes bibliographical references and index.
Contents:
Tumor staging and grading : a primer -- Clinical trial design in the age of molecular profiling -- Personalized medicine : ethics for clinical trials -- Reduction of preanalytical variability in specimen procurement for molecular profiling -- The human side of cancer biobanking -- Introduction to genomics -- Genomic profiling : cDNA arrays and oligoarrays -- Genome-wide methylation profiling in archival formalin-fixed paraffin-embedded tissue samples -- An overview of microRNA methods : expression profiling and target identification -- Antibody validation by western blotting -- Laser capture microdissection : Arcturus(XT) infrared capture and UV cutting methods -- Antibody microarrays : Analysis of cystic fibrosis -- Tissue microarrays as a tool in the discovery and validation of predictive biomarkers -- Reverse-phase protein microarrays -- Serum low-molecular-weight protein fractionation for biomarker discovery -- Mass spectrometry-based biomarker discovery -- Mitochondrial proteome : toward the detection and profiling of disease associated alterations -- Adult neural stem cells : Isolation and propagation -- Evanescent-wave field imaging : an introduction to total internal reflection fluorescence microscopy -- Construction and hyperspectral imaging of quantum dot lysate arrays -- Microarray data analysis : comparing two population means -- Bioinformatics/biostatistics : microarray analysis -- Structure-based functional design of drugs : from target to lead compound -- Personalized medicine : changing the paradigm of drug development -- Grant writing tips for translational research -- Inventions and patents : a practical tutorial -- Regulatory approval pathways for molecular diagnostic technology -- Small business development for molecular diagnostics.
Series:
Methods in molecular biology, 1064-3745 ; 823
Springer protocols
ISBN:
9781603272162 (ebk.)
160327216X (ebk.)
9781603272155
1603272151
OCLC:
(OCoLC)751520051
Locations:
OVUX522 -- University of Iowa Libraries (Iowa City)

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