Hormonal smartphone diagnostics / P. R. Matias-Garcia, J. L. Martinez-Hurtado, A. Beckley, M. Schmidmayr, and V. Seifert-Klauss. Effects of prenatal nutrition and the role of the placenta in health and disease / Leslie Myatt and Kent L. Thornburg -- Developmental origins of stress and psychiatric disorders / Francesca L. Guest and Paul C. Guest -- Proteomic studies of psychiatric disorders / Paul C. Guest -- Developmental origins of breast cancer : a paternal perspective / Camile Castilho Fontelles, Raquel Santana da Cruz, Leena Hilakivi-Clarke, Sonia de Assis, and Thomas Prates Ong -- Point-of-care testing and personalized medicine for metabolic disorders / Francesca L. Guest and Paul C. Guest -- Pregnancy and lactation : a window of opportunity to improve individual health / Guadalupe L. Rodrıguez-Gonza lez, Diana C. Castro-Rodrıguez, and Elena Zambrano -- Utility of small animal models of developmental programming / Clare M. Reynolds and Mark H. Vickers -- Generation of maternal obesity models in studies of developmental programming in rodents / Paul D. Taylor, Phillippa A. Matthews, Imran Y. Khan, Douglas Rees, Nozomi Itani, and Lucilla Poston -- Generation of the maternal low-protein rat model for studies of metabolic disorders / Dan Ma, Susan E. Ozanne, and Paul C. Guest -- Investigation of paternal programming of breast cancer risk in female offspring in rodent models / Camile Castilho Fontelles, Raquel Santana da Cruz, Leena Hilakivi-Clarke, Sonia de Assis, and Thomas Prates Ong -- Studies of isolated peripheral blood cells as a model of immune dysfunction / Hassan Rahmoune and Paul C. Guest -- Studies of a neuronal cell line as a model of psychiatric disorders / Keiko Iwata -- Assessment of placental transport function in studies of disease programming / Amanda N. Sferruzzi-Perri -- Assessment of fatty liver in models of disease programming / Kimberley D. Bruce and Karen R. Jonscher -- Capillary blood sampling from the finger / Kieron Rooney -- Physical activity assessment in clinical studies of substance use disorder / Rhiannon Dowla, Bridin Murnion, Kia Roberts, Jonathan Freeston, and Kieron Rooney -- Cardiopulmonary exercise testing / Derek Tran -- Cardiovascular assessment in human research / Marjan Mosalman Haghighi and Julian Ayer -- Nutritional programming effects on the immune system / Donald B. Palmer -- Small RNA sequencing : a technique for miRNA profiling / Lucas Carminatti Pantaleao and Susan E. Ozanne -- Pulse-chase biosynthetic radiolabeling of Pancreatic Islets to Measure Beta Cell Function / Paul C. Guest -- Rapid and easy protocol for quantification of next-generation sequencing libraries / Steve F. C. Hawkins and Paul C. Guest -- Telomere length analysis : a tool for dissecting aging mechanisms in developmental programming / Jane L. arry-Adkins and Susan E. Ozanne -- Qualitative and qantitative NMR approaches in blood serum lipidomics / Banny Silva Barbosa, Lucas Gelain Martins, Tassia B. B. C. Costa, Guilherme Cruz, and Ljubica Tasic -- In vivo electrical stimulation for the assessment of skeletal muscle contractile function in murine models / Kaio F. Vitzel, Marco A. Fortes, Gabriel Nasri Marzuca-Nassr, Maria V.M. Scervino, Carlos H. Pinheiro, Leonardo R. Silveira, and Rui Curi -- Experimental model of skeletal suscle laceration in rats / Phablo Abreu, Gabriel Nasri Marzuca-Nassr, Sandro Massao Hirabara, and Rui Curi -- Neuropsychiatric sequelae of early nutritional modifications : a beginner's guide to behavioral analysis / Ann-Katrin Kraeuter, Paul C. Guest, and Zoltan Sarnyai -- Hyperlocomotion test for assessing behavioral disorders / Dan Ma and Paul C. Guest -- 2D-DIGE analysis of eye lens proteins as measure of cataract formation / Paul C. Guest -- Mass spectrometry profiling of pituitary glands / Divya Krishnamurthy, Hassan Rahmoune, and Paul C. Guest -- Multiplex immunoassay profiling of hormones involved in metabolic regulation / Laurie Stephen and Paul C. Guest -- Time-resolved fluorescence assays for quantification of insulin precursors in plasma and serum / Kevin Taylor, Ian Halsall, Paul C. Guest, and Keith Burling -- Identification of neural stem cell biomarkers by isobaric tagging for relative and absolute quantitation (iTRAQ) mass spectrometry / Paul C. Guest -- Lab-on-a-chip device for rapid measurement of vitamin D levels / Harald Peter, Nikitas Bistolas, Soeren Schumacher, Cecilia Laurisch, Paul C. Guest, Ulrich Holler, and Frank F. Bier -- Kidney smartphone diagnostics / P. R. Matias-Garcia and J. L. Martinez-Hurtado -- User-friendly app for blood coagulation disorders / Johannes Vegt and Paul C. Guest -- Hormonal smartphone diagnostics / P. R. Matias-Garcia, J. L. Martinez-Hurtado, A. Beckley, M. Schmidmayr, and V. Seifert-Klauss.
Summary:
This volume contains several reviews in the field as well as the step-by-step use of targeted and global approaches within the areas of genomics, epigenetics, proteomics, transcriptomics and metabolomics which aim to address this dilemma and to help pinpoint new treatment strategies. Chapters detail the generation of several models and methods for assessing health and provide researchers potential approaches for reversing or minimizing effects of disease. In addition, important information on disease mechanisms is provided, as each method is described in the context of a specific disease or therapeutic area. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Investigations of Early Nutrition Effects on Long-Term Health: Methods and Applications aim is to provide insights into the latest ideas and technologies .enabling progress in this field.
Series:
Methods in molecular biology, 1064-3745 ; v. 1735 Springer protocols, 1949-2448
This resource is supported by the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act as administered by State Library of Iowa.