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Title:
Genetic toxicology : principles and methods / edited by James M. Parry and Elizabeth M. Parry.
Publisher:
Humana Press,
Copyright Date:
c2012
Description:
xvi, 433 p. : ill. (some col.) ; 27 cm.
Subject:
Genetic toxicology.
Mutagenicity testing.
Mutagenicity Tests--Laboratory Manuals.
Mutagens--Laboratory Manuals.
Other Authors:
Parry, J. M.
Parry, Elizabeth M.
Notes:
Includes bibliographical references and index.
Contents:
The application of structure-activity relationships to the prediction of the mutagenic activity of chemicals / Philip Judson -- Bacterial mutagenicity assays : test methods / David Gatehouse -- The mouse lymphoma assay / Melvyn Lloyd and Darren Kidd -- Mammalian cell HPRT gene mutation assay : test methods / George E. Johnson -- The in vitro mammalian chromosome aberration test / Gill Claire -- The interpretation and analysis of cytogenetic data / Natalie Danford -- The in vitro micronucleus assay / Ann T. Doherty -- The in vitro and in vivo comet assays / Brian Burlinson -- Assessment of DNA interstrand crosslinks using the modified alkaline comet assay / Jian Hong Wu and Nigel J. Jones -- ³²P-postlabelling for the sensitive detection of DNA adducts / Nigel J. Jones -- Methods for the detection of DNA adducts / Karen Brown -- The GADD45a-GFP GreenScreen HC assay / Richard M. Walmsley and Matthew Tate -- Real-time reverse-transcription polymerase chain reaction : technical considerations for gene expression analysis / Shareen H. Doak and Zoulikha M. Zaïr -- Cytogenetic in vivo assays in somatic cells / Ann T. Doherty, Adi Baumgartner, and Diana Anderson -- Cytogenetic methods in human biomonitoring : principles and uses / Raluca A. Mateuca, Ilse Decordier, and Micheline Kirsch-Volders -- The measurement of induced genetic change in mammalian germ cells / Ilse-Dore Adler, Francesca Pacchierotti, and Antonella Russo -- Transgenic animal mutation models : a review of the models and how they function / Steve Dean -- Analysis of genotoxicity data in a regulatory context / Ian de G. Mitchell and David O.F. Skibinski.
Series:
Methods in molecular biology, 1064-3745 ; 817
Springer protocols
ISBN:
161779421X (ebk.)
9781617794216 (ebk.)
1617794201 (alk. paper)
9781617794209 (alk. paper)
OCLC:
(OCoLC)751836104
LCCN:
2011942910
Locations:
OVUX522 -- University of Iowa Libraries (Iowa City)

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