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Title:
Cell-penetrating peptides : methods and protocols / edited by Ülo Langel.
Publisher:
Humana Press,
Copyright Date:
c2011
Description:
xv, 586 p. : ill. (some col.) ; 27 cm.
Subject:
Peptides--Physiological transport.
Drug carriers (Pharmacy)
Peptides--pharmacokinetics--Laboratory Manuals.
Biological Transport--physiology--Laboratory Manuals.
Drug Carriers--Laboratory Manuals.
Other Authors:
Langel, Ülo.
Notes:
Includes bibliographical references and index.
Contents:
Classes and prediction of cell-penetrating peptides / Maria Lindgren and Ülo Langel -- Penetratin story : an overview / Edmond Dupont, Alain Prochiantz, and Alain Joliot -- Testing membrane interactions of CPPs / Astrid Gräslund and Lena Mäler -- Interactions of amphipathic CPPs with model membranes / Sébastien Deshayes ... [et al.] -- NMR studies of three-dimensional structure and positioning of CPPs in membrane model systems / Lena Mäler and Astrid Gräslund -- Measurements of the intracellular stability of CPPs / Ivo R. Ruttekolk ... [et al.] -- Tools for predicting binding and insertion of CPPs into lipid bilayers / Paulo F. Almeida -- Studies of proteoglycan involvement in CPP-mediated delivery / Anders Wittrup, Si-He Zhang, and Mattias Belting -- Uptake kinetics of cell-penetrating peptides / Anders Florén, Imre Mäger, and Ülo Langel -- Thermodynamics of lipid interactions with cell-penetrating peptides / Reto Sauder, Joachim Seelig, and André Ziegler --
Calcium and membrane repair / Caroline Palm-Apergi and Mattias Hällbrink -- Mapping of protein transduction pathways with fluorescent microscopy / Helin Räägel ... [et al.] -- Insight into cell-entry mechanisms of CPPs by electron microscopy / Kärt Padari ... [et al.] -- Toxicity methods for CPPs / Per Lundin, Samir EL Andaloussi, and Ülo Langel -- Comparison of CPP uptake methods / Tina Holm, Samir EL Andaloussi, and Ülo Langel -- Characterization of cellular internalization pathways for CPP-mediated oligonucleotide delivery / Peter Guterstam, Samir EL Andaloussi, and Ulo Langel -- Mimicry of protein function with cell-penetrating peptides / Henrik J. Johansson, Samir EL Andaloussi, and Ülo Langel -- Homeoprotein intercellular transfer, the hidden face of cell-penetrating peptides / Alain Prochiantz -- Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models / Sarah L. Tressel ... [et al.] --
Identification and characterization of tissue-specific protein transduction domains using peptide phage display / Maliha Zahid and Paul D. Robbins -- Applications of cell-penetrating peptides as signal transduction modulators for the selective induction of apoptosis / Sarah Jones and John Howl -- Splice redirection as a convenient assay to monitor CPP-ON efficiency and mechanism Rachida Abes ... [et al.] -- CPP-directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy / HaiFang Yin ... [et al.] -- PTD-DRBD siRNA delivery Caroline Palm-Apergi, Akiko Eguchi, and Steven F. Dowdy -- A non-covalent peptide-based strategy for siRNA delivery / Laurence Crombez and Gilles Divita -- Application of PepFect peptides for the delivery of splice-correcting oligonucleotides / Samir EL Andaloussi ... [et al.] -- Internalization of nucleoside phosphates into live cells by complex formation with different CPPs and JBS-nucleoducin / Franziska Mussbach ... [et al.] --
Enhanced cellular delivery of cell-penetrating peptide-peptide nucleic acid conjugates by photochemical internalization / Takehiko Shiraishi and Peter E. Nielsen -- Identification of homing peptides using the in vivo phage display technology / Antti Rivinoja and Pirjo Laakkonen -- Measuring the action of CPP-siRNA conjugates in the lung / Sterghios A. Moschos, Karen G. Spink, and Mark A. Lindsay -- Intracellular delivery of nanoparticles with CPPs / Rupa Sawant and Vladimir Torchilin -- Multifunctional CPP polymer system for tumor-targeted pDNA and siRNA delivery / Christian Dohmen and Ernst Wagner -- Cell-penetrating penta-peptides and bax-inhibiting peptides : protocol for their application / Jose Gomez and Shigemi Matsuyama -- PAIR technology : exon-specific RNA-binding protein isolation in live cells / Thomas J. Bell ... [et al.] -- Quantitation of cellular and topical uptake of luciferin-oligoarginine conjugates / Jonathan B. Rothbard and Lisa R. Jones --
Industrial-scale manufacturing of a possible oligonucleotide cargo CPP-based drug / Ulf Tedebark ... [et al.] -- Application of a fusiogenic peptide GALA for intracellular delivery / Ikuhiko Nakase ... [et al.] -- Therapeutic applications of cell-penetrating peptides / Randolph M. Johnson, Stephen D. Harrison, and Derek Maclean -- Nonclinical and clinical experiences with CPP-based self-assembling peptide systems in topical drug development / Jacob M. Waugh ... [et al.].
Series:
Springer protocols
Methods in molecular biology, 1064-3745 ; v. 683
ISBN:
1607619180 (alk. paper)
9781607619185 (alk. paper)
OCLC:
(OCoLC)648933039
LCCN:
2010938786
Locations:
OVUX522 -- University of Iowa Libraries (Iowa City)

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