"This volume is the result of the conference on Tumor progression and therapeutic resistance, held November 8-9, 2004, in Philadelphia, Pennsylvania"--P. [v]. Includes bibliographical references and index.
Contents:
Tumor progression and therapeutic resistance: an overview / Linda Hotchkiss Mehta -- Proteomics in tumor progression and metastasis / Patrick A. Everley and Bruce R. Zetter -- Cytoplasmic/nuclear shuttling and tumor progression / Shao-Chun Wang and Mien-Chie Hung -- Targeting intracellular signaling pathways as a novel strategy in melanoma therapeutics / Keiran S.M. Smalley and Meenhard Herlyn -- Studies into the anticancer effects of selenomethionine against human colon cancer / Mark A. Nelson ... [et al.] -- Mechanisms of prostate tumorigenesis: roles for transcription factors Nkx3.1 and Egr1 / Sarki A. Abdulkadir -- Sulindac sulfone is most effective in modulating (beta)-catenin-mediated transcription in cells with mutant APC / Wen-Chi L. Chang ... [et al.] -- Targeting ligand cleavage to inhibit the ErbB pathway in cancer / Bin-Bing S. Zhou -- Preclinical modeling of combination treatments: fantasy or requirement? / Shannon Decker and Edward A. Sausville -- Mechanisms of trastuzumab resistance and their clinical implications / Keng-Hsueh Lan, Chien-Hsing Lu, and Dihua Yu -- Regulation of cancer cell survival by Par-4 / Padhma Ranganathan and Vivek M. Rangnekar -- Morphogenics as a tool for target discovery and drug development / Nicholas C. Nicolaides ... [et al.] -- A comprehensive strategy to combat colon cancer targeting the adenomatous polyposis coli tumor suppressor gene / Eugene W. Gerner ... [et al.] -- External imaging of CCND1, MYC, and KRAS oncogene mRNAs with tumor-targeted radionuclide-PNA-peptide chimeras / Xiaobing Tian ... [et al.] -- Functional validation of genes implicated in lymphomagenesis: an in vivo selection assay using a MYC-induced B-cell tumor / Duonan Yu ... [et al.] -- The proteasome inhibitor bortezomib (velcade) sensitizes some human tumor cells to Apo2L/TRAIL-mediated apoptosis / Alan D. Brooks ... [et al.] -- The role of tuberin in cellular differentiation: are B-Raf and MAPK involved? / Magdalena Karbowniczek and Elizabeth Petri Henske -- A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma / Ching Ching Leow, Paul Polakis, and Wei-Qiang Gao -- Alterations in DNA repair gene expression under hypoxia: elucidating the mechanisms of hypoxia-induced genetic instability / Ranjit S. Bindra ... [et al.].
Series:
Annals of the New York Academy of Sciences ; v. 1059
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