NGS for sequence variants / Shaolei Teng -- RNA bioinformatics for precision medicine / Jiajia Chen, Bairong Shen -- Exploring human diseases and biological mechanisms by protein structure prediction and modeling / Juexin Wang, Joseph Luttrell IV, Ning Zhang, Saad Khan, NianQing Shi, Michael X. Wang, Jing-Qiong Kang, Zheng Wang, and Dong Xu -- Computational methods in mass spectrometry-based proteomics / Sujun Li, Haixu Tang -- Informatics for metabolomics / Kanthida Kusonmano, Wanwipa Vongsangnak, Pramote Chumnanpuen -- Metagenomics and single-cell omics data analysis for human microbiome research / Maozhen Han, Pengshuo Yang, Hao Zhou, Hongjun Li, Kang Ning -- Text mining for precision medicine: bringing structure to EHRs and biomedical literature to understand genes and health / Michael Simmons, Ayush Singhal, Zhiyong Lu -- Medical imaging informatics / William Hsu Ph.D, Suzie El-Saden, Ricky K. Taira -- LIMS and clinical data management / Yalan Chen, Yuxin Lin, Xuye Yuan, Bairong Shen -- Biobanks and their clinical application and informatics challenges / Lan Yang, Yalan Chen, Chunjiang Yu, Bairong Shen -- XML, ontologies, and their clinical applications / Chunjiang Yu, Bairong Shen -- Bayesian computation methods for inferring regulatory network models using biomedical data / Tianhai Tian -- Network-based biomedical data analysis / Yuxin Lin, Xuye Yuan, Bairong Shen.
Summary:
"This book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level -- e.g. different omics data at the molecular level -- but also data from different levels -- the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics"--Publisher's description.
Series:
Advances in experimental medicine and biology, 0065-2598 ; volume 939
This resource is supported by the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act as administered by State Library of Iowa.