Chapter 1. Emergence of nanotherapeutics : challenges in classical drug transport versus macromolecular drug design -- chapter 2. The ultimate destinations for delivery and release of nanotherapeutics -- chapter 3. Diversity of bioactive nanoparticles from biological, chemical, and physical perspectives -- chapter 4. Fabrication strategies for biofunctional nanoparticles -- chapter 5. Interactions and orientation of therapeutic drugs in the vicinity of nanoparticles -- chapter 6. Variable interactions of nanoparticles with blood, lymph, and extracellular and intracellular components -- chapter 7. Pharmacokinetics and biodistribution of nanoparticles -- chapter 8. Specific roles of nanoparticles in various steps of drug transport -- chapter 9. Nanotechnology approaches to modulate transport, release, and bioavailability of classical and emerging therapeutics -- chapter 10. Nanotechnology in the development of innovative treatment strategies -- chapter 11. Nanoparticles for therapeutic delivery in animal models of different cancers -- chapter 12. Nanoparticles for therapeutic delivery in animal models of other critical human diseases -- chapter 13. Nanomedicine in clinical trials -- chapter 14. Approved and commercialized nanomedicine -- chapter 15. Current safety issues : biodegradability, reactivity, and clearance.
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