Sect. I. Holistic science on matter, life, and consciousness. Twenty fundamental problems of biology, medicine, and neuropsychology related to biological information -- We need an integrated theory for matter, life and consciousness to understand life and healing -- Bridging brain-mind and body-mind. Introduction to "deep" (fractal, poly-ray) cosmology -- The living cell has information-directed self-organization -- Biochemistry unable to explain the emergence of biological form (morphogenesis) and therefore a new principle as source of biological information is needed -- Supracellular morphogenesis: the origin of biological and cellular order -- A spiral fractal model of fine structure of physical energy could explain central aspects of biological information, biological organization and biological creativity -- A theory of "deep" quantum chemistry and cell consciousness -- The wholenessof man, his consciousness and collective consciousness -- Explanation of macroevolution -- top-down evolution materializes consciousness. The origin of metamorphosis -- the human brain: the structure of the cerebral cortex. are there really modules in the brain? A theory for the structure and function of the human brain -- Sect. 2. Patient-related outcome measures. The safe and efficient medical clinic -- Square curve paradigm -- Clinical quality-assurance and research on treatment efficacy and safety -- Sect. 3. Politics and economy. What is going on in the world? -- Is the randomised clinical trial (RCT) really the gold standard? -- Comparative analysis of cost-effectiveness of non-drug medicine and biomedicine for all clinical conditions -- Cost-effectiveness of non-drug medicine and pharmaceutical biomedicine in QALY -- Use of coercive persuasion ("brainwashing," "mind control") in psychiatry from an ethical point of view -- Bio- and alternative medicine in conflict. Human rights protection of alternative therapist -- Sect. 4. Acknowledgments. About the authros -- International review board -- About the Quality of Life Research Center in Copenhagen, Denmark -- About the National Institute of Child Health and Human Development in Israel.
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