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Title:
Computer applications in pharmaceutical research and development / [edited by] Sean Ekins.
Publisher:
Wiley-Interscience,
Copyright Date:
2006
Description:
xix, 805 pages, 12 unnumbered pages of plates : illustrations (some color) ; 25 cm.
Subject:
Pharmacy--Data processing.
Pharmacology--Data processing.
Pharmaceutical industry--Data processing.
Drug Industry.
Medical Informatics.
Drug Approval--methods.
Drug Evaluation--methods.
Drug Evaluation, Preclinical--methods.
Other Authors:
Ekins, Sean. http://id.loc.gov/authorities/names/n2005184735
Notes:
Includes bibliographical references and index.
Contents:
The history of computers in pharmaceutical research and development : a narrative / Donald B. Boyd and Max M. Marsh -- Computers as data analysis and data management tools in preclinical development / Weiyong Li and Kenneth Banks -- Statistical modeling in pharmaceutical research and development / Andrea de Gaetano ... [et al.] -- Drug discovery from historic herbal texts / Eric J. Buenz -- Contextualizing the impact of bioinformatics on preclinical drug and vaccine discovery / Darren R. Flower -- Systems approaches for pharmaceutical research and development / Sean Ekins and Craig Giroux -- Information management-biodata in life sciences / Richard K. Scott and Anthony Parsons -- Chemoinformatics techniques for processing chemical structure databases / Valerie J. Gillet and Peter Willett -- Electronic laboratory notebooks / Alfred Nehme and Robert A. Scoffin -- Strategies for using information effectively in early-stage drug discovery / David J. Wild -- Improving the pharmaceutical R&D process : how simulation can support management decision making / Andrew Chadwick ... [et al.] --
Computers and protein crystallography / David J. Edwards and Roderick E. Hubbard -- Computers, cheminformatics, and the medicinal chemist / Weifan Zheng and Michael Jones -- The challenges of making useful protein-ligand free energy predictions for drug discovery / Jun Shimada -- Computer algorithms for selecting molecule libraries for synthesis / Konstantin V. Balakin, Nikolay P. Savchuk, and Alex Kiselyov -- Success stories of computer-aided design / Hugo Kubinyi -- Pharmaceutical research and development productivity : can software help? / Christophe Lambert and S. Stanley Young -- Computer methods for predicting drug metabolism / Sean Ekins -- Computers in toxicology and risk assessment / John C. Dearden -- Computational modeling of drug disposition / Cheng Chang and Peter W. Swaan -- Computer simulations in pharmacokinetics and pharmacodynamics: rediscovering systems physiology in the 21st century / Paolo Vicini -- Predictive models for better decisions from understanding physiology to optimizing trial design / James R. Bosley, Jr --
Making pharmaceutical development more efficient / Michael Rosenberg and Richard Farris -- Use of interactive software in medical decision making / ReneĢe J. Goldberg Arnold -- Clinical data collection and management / Mazen Abdellatif -- Regulation of computer systems / Sandy Weinberg -- A new paradigm for analyzing adverse drug events / Ana Szarfman, Jonathan G. Levine and Joseph M. Tonning -- Computers in pharmaceutical formulation / Raymond C. Rowe and Elizabeth A. Colbourn -- Legal protection of innovative uses of computers in R&D / Robert Harrison -- The ethics of computing in pharmaceutical research / Matthew K. McGowan and Richard J. McGowan -- The UltraLink : an expert system for contextual hyperlinking in knowledge management / Martin Romacker ... [et al.] -- Powerful, predictive and pervasive : the future of computers in the pharmaceutical industry / Nick Davies, Heather Ahlborn, Stuart Henderson.
Series:
Wiley series in drug discovery and development
ISBN:
9780471737797
0471737798
OCLC:
(OCoLC)62381270
LCCN:
2005033608
Locations:
OVUX522 -- University of Iowa Libraries (Iowa City)

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