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Title:
Toll-like receptors : methods and protocols / edited by Claire E. McCoy, Luke A.J. O'Neill.
Publisher:
Humana Press,
Copyright Date:
2009
Description:
xiv, 447 pages, 4 unnumbered pages of plates : illustrations (some color) ; 27 cm.
Subject:
Cell receptors.
Cellular immunity.
Toll-Like Receptors.
Laboratory Manuals.
Other Authors:
McCoy, Claire E. http://id.loc.gov/authorities/names/n2009181886
O'Neill, Luke A. J. http://id.loc.gov/authorities/names/n95000042
Notes:
Includes bibliographical references and index.
Contents:
Expression analysis of the toll-like receptors in human peripheral blood mononuclear cells / Jakub Siednienko and inead M. Miggin -- Ligands, cell-based models, and readouts required for toll-like receptor action / Jérôme Dellacasagrande -- Toll-like receptor interactions imaged by FRET microscopy and GFP fragment reconstitution / Gabor Horvath, Scott Young, and Eicke Latz -- Predicting toll-like receptor structures and characterizing ligand binding / Joshua N. Leonard, Jessica K. Bell, and David M. Segal -- Bioinformatic analysis of toll-like receptor sequences and structures / Tom P. Monie, Nicholas J. Gay, and Monique Gangloff -- Expression, purification, and crystallization of toll/interleukin-1 receptor (TIR) domains / Xiao Tao and Liang Tong -- Proteomic analysis of protein complexes in toll-like receptor biology / Kiva Brennan and Caroline A. Jefferies -- 2D-DIGE : comparative proteomics of cellular signalling pathways / Nadia Ben Larbi and Caroline Jefferies --
MAPPIT (mammalian protein-protein interaction trap) analysis of early steps in toll-like receptor signalling / Peter Ulrichts ... [et al.] -- Analysis of the functional role of toll-like receptor-4 tyrosine phosphorylation / Andrei E. Medvedev and Wenji Piao -- Analysis of ubiquitin degradation and phosphorylation of proteins / Pearl Gray --The generation of highly purified primary human neutrophils and assessment of apotosis in response to toll-like receptor ligands / Lisa C. Parker ... [et al.] -- Cellular expression of A20 and ABIN-3 in response to toll-like receptor-4 stimulation / Kelly Verhelst ... [et al.] -- Characterisation of viral proteins that inhibit toll-like receptor signal transduction / Julianne Stack and Andrew G. Bowie -- Genetic dissection of toll-like receptor signaling using ENU mutagenesis / Kasper Hoebe -- Microarray experiments to uncover toll-like receptor function / Harry Björbacka --
Uncovering novel gene function in toll-like receptor signalling using siRNA / Michael Carty, Sinéad Keating, and Andrew Bowie -- Genotyping methods to analyse polymorphisms in toll-like receptors and disease / Chiea-Chuen Khor -- Experimental models of acute infection and toll-like receptor driven septic shock / Ruth Ferstl ... [et al.] -- Toll-like receptors and rhematoid arthritis / Fabia Brentano, Diego Kyburz, and Steffen Gay -- Practical techniques for detection of toll-like receptor-4 in the human intestine / Ryan Ungaro, Maria T. Abreu, and Masayuki Fukata -- Toll-like receptor-dependent immune complex activation of B cells and dendritic cells / Melissa B. Uccellini ... [et al.] -- Innate immunity, toll-like receptors, and atherosclerosis : mouse models and methods / Rosalinda Sorrentino and Moshe Arditi -- Generation of parasite antigens for use in toll-like receptor research / Philip Smith, Niamh E. Mangan, and Padraic G. Fallon --
Biomarkers measuring the activity of toll-like receptor ligands in clinical development programs / Paul Sims, Robert L. Coffman, and Edith M. Hessel.
Series:
Springer protocols
Methods in molecular biology, 1064-3745 ; 517
ISBN:
193411572X
9781934115725
OCLC:
(OCoLC)261955183
LCCN:
2008943238
Locations:
OVUX522 -- University of Iowa Libraries (Iowa City)

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