Utilizing direct analysis in real time-high resolution mass spectrometry-derived dark matter spectra to classify and identify unknown synthetic cathinones / Kristen L. Fowble and Rabi A. Musah. Illicit and counterfeit drug analysis by morphologically directed raman spectroscopy / Andrew C. Koutrakos, Pauline E. Leary, and Brooke W. Kammrath -- Analysis of drugs abuse by gas chromatography-mass spectrometry (GC-MS) / Thomas A. Brettell and Benny J. Lum -- Toward confirmatory on-site real-time detection of emerging drugs using portable ultrafast capillary electrophoresis mass spectrometry / Mehdi Moini -- Use of DART-TOF-MS for screening drugs of abuse / Robert R. Steiner -- Confirmation of pharmaceutical identifiers via DART-TOF-MS / Jacob Easter -- UPLC-Orbitrap® screening for over 35 drugs of abuse and metabolites in biological fluids in under 10 min / Eshwar Jagerdeo and Jason E. Schaff -- Sensitivity enhancement in capillary electrophoresis using magnetic particles as solid-phase extraction sorbents for the determination of drugs of abuse in urine / Tatiana Baciu, Francesc Borrull, Carme Aguilar, and Marta Calull -- High-throughput extraction and detection of drugs in urine : parallel sampling with solid-phase microextraction (SPME) fibers coupled with direct analysis in real time-mass spectrometry (DART-MS) detection / Frederick Li and Brian Musselman -- Analysis of drugs of abuse in hair samples by ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) / D. Di Corcia, A. Salomone, and E. Gerace -- Comprehensive drug screening by thermal desorption and pyrolysis combined with direct analysis in real time-mass spectrometry (TDP/DART-MS) / Hiroko Abe, Chikako Takei, Motoshi Sakakura, Daisuke Yajima, and Hirotato Iwase -- Detection of diagnostic plant-derived psychoactive biomarkers in fingerprints by MALDI-SpiralTOF-mass spectrometry imaging / Cameron M. Longo and Rabi A. Musah -- Matrix-assisted laser desorption ionization imaging mass spectrometry of drug distribution in mouse brain tissue by high-resolution time-of-flight mass spectrometry / Takaya Satoh, Ayumi Kubo, and Hisanao Hazama -- Estimation of community usage of drugs utilizing sewage epidemiology / Bikram Subedi -- LC-MS-MS method development and analysis of stimulants, opiates, synthetic opiates, PCP, and benzodiazepines in wastewater. Preponderance of these drugs during football games / Waseem Gul, Shahbaz W. Gul, Brandon Stamper, Murrell Godfrey, and Mahmoud A. ElSohly -- Analysis of Illicit drugs in wastewater using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS) / Katelyn S. Foppe and Bikram Subedi -- Analysis of trace drugs of abuse by direct analysis in real time (DART) mass spectrometry / David D. Cunningham -- Rapid, high-throughput validated method for the quantification of atropine in Datura stramonium seeds using direct analysis in real time-high resolution mass spectrometry (DART-HRMS) / Ashton D. Lesiak, Kristen L. Fowble, and Rabi A. Musah -- Utilizing direct analysis in real time-high resolution mass spectrometry-derived dark matter spectra to classify and identify unknown synthetic cathinones / Kristen L. Fowble and Rabi A. Musah.
Summary:
This volume features a comprehensive set of protocols featuring a range of both old and new technologies that can be used to analyze drugs of abuse, including prescription drugs, new psychoactive substances and psychoactive plants. Chapters guide readers through the application of color tests, light microscopy-based particle imaging, GC-MS, Raman spectroscopy, capillary electrophoresis, ultra-high performance LC-tandem MS, DART-MS, MALDI-mass spectrometry imaging, LC-MS/MS and HPLC-ESI-MS/MS to the analysis of abused drugs in wastewater, hair, urine and plant-derived materials, among other matrices. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Analysis of Drugs of Abuse aims to ensure successful results in the further study of this vital field.
Series:
Methods in molecular biology, 1064-3745 ; 1810 Springer protocols, 1949-2448
This resource is supported by the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act as administered by State Library of Iowa.