Lung cancer statistics / Lindsey A. Torre, Rebecca L. Siegel, and Ahmedin Jemal -- Epidemiology of lung cancer / Ann G. Schwartz and Michele L. Cote -- Lung cancer in never smokers / Gabriel Alberto Rivera and Heather Wakelee -- Immune therapy / Lysanne Lievense, Joachim Aerts, and Joost Hegmans -- Anti-angiogenesis in personalized therapy of lung cancer / Peter M. Ellis -- Target therapy in lung cancer / Stefano Cafarotti, Filippo Lococo, Patrizia Froesh, Francesco Zappa, and Dutly AndreĢ -- Mechanisms of resistance to EGFR tyrosine kinase inhibitors and therapeutic approaches: an update / Aarif Ahsan -- KRAS-Mutant lung cancers in the era of targeted therapy / Jarushka Naidoo and Alexander Drilon -- Anaplastic Lymphoma Kinase (ALK) signaling in lung cancer / Sai-Hong Ignatius Ou and Keisuke Shirai -- Chemotherapy resistance in lung cancer / Eric S. Kim -- Current state of metal-based drugs for the efficient therapy of lung cancers and lung metastases / Bernhard Biersack and Rainer Schobert.
Summary:
"This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer--statistics and epidemiology of lung cancer--along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer--immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogenesis; the associated challenges, especially resistance mechanisms; and recent progress in targeted drug development based on metal chemistry. Chapters are written by some of the leading experts in the field, who provide a better understanding of lung cancer, the factors that make it lethal, and current research focused on developing personalized treatment plans. With a unique mix of topics, this volume summarizes the current state-of-knowledge on lung cancer and the available therapies"--Back cover.
Series:
Advances in experimental medicine and biology, 0065-2598 ; 893
This resource is supported by the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act as administered by State Library of Iowa.