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07425aam a2200553 i 4500 001 DFA21C8E083E11EABF3FA51A97128E48 003 SILO 005 20191116010051 008 151211t20172017paua b 001 0 eng 010 $a 2015048962 020 $a 1496320573 020 $a 9781496320575 020 $a 1451191006 020 $a 9781451191004 035 $a (OCoLC)914593652 040 $a DNLM/DLC $b eng $e rda $c DLC $d YDX $d BTCTA $d YDXCP $d NLM $d OCLCF $d IAX $d NRC $d SISPL $d CUV $d OCLCO $d OCLCA $d MMV $d OHS $d MMU $d GTA $d OCLCQ $d UtOrBLW $d SILO 042 $a pcc 050 10 $a RM301 $b .P65 2017 060 00 $a 2016 E-274 060 10 $a QV 38 082 00 $a 615/.1 $2 23 130 0 $a Principles of pharmacology (Golan) 245 10 $a Principles of pharmacology : $b the pathophysiologic basis of drug therapy / $c David E. Golan, MD, PhD, editor in chief ; Ehrin J. Armstrong, MD, MSc, April W. Armstrong, MD, MPH, associate editors. 250 $a Fourth edition. 264 1 $a Philadelphia : $b Wolters Kluwer, $c [2017] 300 $a xix, 1,020 pages : $b illustrations (some color) ; $c 28 cm 504 $a Includes bibliographical references and index. 505 00 $g 7. $g 1. $t Pharmacogenomics / $r Kelan Tantisira. $g 2. $t Pharmacodynamics / $r David E. Golan -- $g 3. $t Pharmacokinetics / $r David E. Golan -- $g 4. $t Drug Metabolism / $r F. Peter Guengerich -- $g 5. $t Drug Transporters / $r Keith A. Hoffmaster -- $g 6. $t Drug Toxicity / $r David E. Golan -- $g 7. $t Pharmacogenomics / $r Kelan Tantisira. 505 00 $g 19. $g SECTION IIA, Fundamental Principles of Neuropharmacology : -- $g 8. $t Pharmacology of Drugs of Abuse / $r Sachin Patel. $g 9. $t Principles of Nervous System Physiology and Pharmacology / $r Daniel H. Lowenstein -- $g SECTION IIB, Principles of Autonomic and Peripheral Nervous System Pharmacology : -- $g 10. $t Cholinergic Pharmacology / $r Gary R. Strichartz -- $g 11. $t Adrenergic Pharmacology / $r David E. Golan -- $g 12. $t Local Anesthetic Pharmacology / $r Gary R. Strichartz -- $g SECTION IIC, Principles of Central Nervous System Pharmacology : -- $g 13. $t Pharmacology of GABAergic and Glutamatergic Neurotransmission / $r Eng H. Lo -- $g 14. $t Pharmacology of Dopaminergic Neurotransmission / $r Victor W. Sung -- $g 15. $t Pharmacology of Serotonergic and Central Adrenergic Neurotransmission / $r Roy H. Perlis -- $g 16. $t Pharmacology of Abnormal Electrical Neurotransmission in the Central Nervous System / $r Daniel H. Lowenstein -- $g 17. $t General Anesthetic Pharmacology / $r Keith W. Miller -- $g 18. $t Pharmacology of Analgesia / $r Clifford J. Woolf -- $g 19. $t Pharmacology of Drugs of Abuse / $r Sachin Patel. 505 00 $g 26. $g 20. $t Integrative Cardiovascular Pharmacology: Hypertension, Ischemic Heart Disease, and Heart Failure / $r Ehrin J. Armstrong. $g 21. $t Pharmacology of Volume Regulation / $r Seth L. Alper -- $g 22. $t Pharmacology of Vascular Tone / $r Joseph Loscalzo -- $g 23. $t Pharmacology of Hemostasis and Thrombosis / $r David E. Golan -- $g 24. $t Pharmacology of Cardiac Rhythm / $r David E. Clapham -- $g 25. $t Pharmacology of Cardiac Contractility / $r Ehrin J. Armstrong -- $g 26. $t Integrative Cardiovascular Pharmacology: Hypertension, Ischemic Heart Disease, and Heart Failure / $r Ehrin J. Armstrong. 505 00 $g 32. $g 27. $t Pharmacology of Bone Mineral Homeostasis / $r Ehrin J. Armstrong. $g 28. $t Pharmacology of the Thyroid Gland / $r William W. Chin -- $g 29. $t Pharmacology of the Adrenal Cortex / $r Gail K. Adler -- $g 30. $t Pharmacology of Reproduction / $r Robert L. Barbieri -- $g 31. $t Pharmacology of the Endocrine Pancreas and Glucose Homeostasis / $r Steven E. Shoelson -- $g 32. $t Pharmacology of Bone Mineral Homeostasis / $r Ehrin J. Armstrong. 505 00 $g 41. $g 33. $t Principles of Combination Chemotherapy / $r David E. Golan. $g 34. $t Pharmacology of Bacterial Infections: DNA Replication, Transcription, and Translation / $r Donald M. Coen -- $g 35. $t Pharmacology of Bacterial and Mycobacterial Infections: Cell Wall Synthesis / $r Sarah P. Hammond -- $g 36. $t Pharmacology of Fungal Infections / $r April W. Armstrong -- $g 37. $t Pharmacology of Parasitic Infections / $r Edward T. Ryan -- $g 38. $t Pharmacology of Viral Infections / $r Donald M. Coen -- $g 39. $t Pharmacology of Cancer: Genome Synthesis, Stability, and Maintenance / $r David A. Frank -- $g 40. $t Pharmacology of Cancer: Signal Transduction / $r David A. Frank -- $g 41. $t Principles of Combination Chemotherapy / $r David E. Golan. 505 00 $g 49. $g 42. $t Integrative Inflammation Pharmacology: Gout / $r Lloyd B. Klickstein. $g 43. $t Pharmacology of Eicosanoids / $r Charles N. Serhan -- $g 44. $t Histamine Pharmacology / $r April W. Armstrong -- $g 45. $t Pharmacology of Hematopoiesis and Immunomodulation / $r George D. Demetri -- $g 46. $t Pharmacology of Immunosuppression / $r April W. Armstrong -- $g 47. $t Integrative Inflammation Pharmacology: Peptic Ulcer Disease / $r Helen M. Shields -- $g 48. $t Integrative Inflammation Pharmacology: Asthma / $r Stephen Lazarus -- $g 49. $t Integrative Inflammation Pharmacology: Gout / $r Lloyd B. Klickstein. 505 00 $g 53. $g 50. $t Systematic Detection of Adverse Drug Events / $r Jerry Avorn. $g SECTION VIII $t Fundamentals of Drug Development and Regulation -- $g 51. $t Drug Discovery and Preclinical Development / $r Maarten Postema -- $g 52. $t Clinical Drug Evaluation and Regulatory Approval / $r Alexander E. Kuta -- $g 53. $t Systematic Detection of Adverse Drug Events / $r Jerry Avorn. 505 00 $g 55. $g 54. $t Drug Delivery Modalities / $r Robert Langer. $g 55. $t Drug Delivery Modalities / $r Robert Langer. 520 $a "Highly regarded by both students and instructors, Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 4th Edition, _offers an integrated mechanism-based and systems-based approach to contemporary pharmacology and drug development. An easy-to-follow format helps first- and second-year students grasp challenging concepts quickly and efficiently. Each chapter presents a clinical vignette illustrating a therapeutic problem within a physiologic or biochemical system; followed by a discussion of the biochemistry, physiology, and pathophysiology of the system; and concluding with a presentation of the pharmacology of_the drugs and drug classes that activate or inhibit the system by interacting with specific molecular and cellular targets. Chapters are integrated into sections that focus on organ systems and therapeutic areas of highest importance. Clear, concise illustrations highlight key points, and drug summary tables offer quick access to essential information"--Publisher's description. 650 0 $a Pharmacology. $0 http://id.loc.gov/authorities/subjects/sh85100599 650 0 $a Physiology, Pathological. $0 http://id.loc.gov/authorities/subjects/sh85101683 650 12 $a Pharmacological Phenomena. $0 https://id.nlm.nih.gov/mesh/D000069437 650 22 $a Drug Therapy. $0 https://id.nlm.nih.gov/mesh/D004358 650 7 $a Pharmacology. $2 fast $0 (OCoLC)fst01060259 650 7 $a Physiology, Pathological. $2 fast $0 (OCoLC)fst01063216 700 1 $a Golan, David E., $e editor. $0 http://id.loc.gov/authorities/names/n2003130175 700 1 $a Armstrong, Ehrin J., $e editor. $0 http://id.loc.gov/authorities/names/n2015191191 700 1 $a Armstrong, April W., $e editor. $0 http://id.loc.gov/authorities/names/n2015191192 776 08 $i Online version: $t Principles of pharmacology. $b Fourth edition. $d Philadelphia : Wolters Kluwer, [2017] $z 9781451191004 $w (OCoLC)952098921 941 $a 1 952 $l OVUX522 $d 20191213023216.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=DFA21C8E083E11EABF3FA51A97128E48Initiate Another SILO Locator Search