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03374aam a22005418i 4500 001 3583104C897C11E3B3ABEFC4DAD10320 003 SILO 005 20200118010508 008 130930s2014 nyu 001 0 eng 010 $a 2013039646 020 $a 1451655673 (trade paperback) 020 $a 9781451655674 (trade paperback) 020 $a 1451655665 (hardback) 020 $a 9781451655667 (hardback) 035 $a (OCoLC)859375019 040 $a DNLM/DLC $b eng $e rda $c DLC $d BTCTA $d BDX $d NLM $d JAG $d SILO 042 $a pcc 050 00 $a RA401.A3 060 10 $a QV 736 AA1 082 00 $a 338.4/76151 $2 23 100 1 $a Werth, Barry, $e author. 245 14 $a The antidote : $b inside the world of new pharma / $c Barry Werth. 250 $a First Simon & Schuster hardcover edition. 263 $a 1402 264 1 $a New York : $b Simon & Schuster, $c 2014. 300 $a p. ; $c cm. 500 $a Includes index. 520 $a "This is the Moneyball of the pharma world, the story of one drug company's quest to transform the pharmaceutical industry and a deeply revealing look into a world where breakneck capitalism meets life-saving medicine.The $325 billion-a-year pharmaceutical business is America's most challenging and one of its most profitable. It is tougher in just about every way than any other enterprise: from the towering biological risks inherent in its mission to treat disease; to the thirty-to-one failure rate in bringing out a successful medicine after a candidate clears all the hurdles to get to human testing; to the billion-dollar-plus cost of ramping up a successful product; to operating in the worlds most highly regulated industry with the possible exception of nuclear power. The Antidote tells the story of Vertex, a maverick drug company led by the charismatic Joshua Boger and a small group of entrepreneurial young scientists who broke off from Merck when it was the world's best drug maker, indeed the most admired business in America because they thought they could make drugs better. Building upon his widely praised The Billion-Dollar Molecule, Barry Werth captures the full scope of Vertex's twenty-five-year drive to liver breakthrough medicines and transform the drug industry. The Antidote draws upon unprecedented inside reporting spanning more than two decades to provide a groundbreaking close-up of Vertex's inner workings and the ferocious but indispensable world it inhabits"--Provided by publisher. 610 22 $a Vertex Pharmaceuticals Incorporated. 650 12 $a Drug Industry $z United States. 650 22 $a Drug Industry $x history $z United States. 650 22 $a History, 20th Century $z United States. 650 22 $a History, 21st Century $z United States. 650 22 $a Technology, Pharmaceutical $z United States. 650 0 $a Pharmaceutical policy $z United States. 650 0 $a Pharmaceutical industry. 610 20 $a Vertex Pharmaceuticals Incorporated. 650 0 $a Pharmaceutical technology. 941 $a 7 952 $l BVPE851 $d 20220728014331.0 952 $l GEPG771 $d 20210722041252.0 952 $l GBPF771 $d 20200701010306.0 952 $l BOPG851 $d 20181006074151.0 952 $l ALPE516 $d 20180523013921.0 952 $l USUX851 $d 20160826085727.0 952 $l CYPF706 $d 20150509011653.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=3583104C897C11E3B3ABEFC4DAD10320 994 $a 92 $b IW9Initiate Another SILO Locator Search