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03291aam a2200541 i 4500 001 66CF092EDB2811ECA7049CC04CECA4DB 003 SILO 005 20220524010218 008 170720t20182017maua b 001 0 eng c 020 $a 9781328915368 020 $a 1328915360 035 $a (OCoLC)994417657 040 $a YDX $b eng $e rda $c YDX $d GSU $d OCLCF $d OQX $d CG4 $d PRSPR $d HRM $d WHCCD $d UPP $d OCLCQ $d UPM $d U@M $d OCLCO $d SILO 042 $a pcc 050 4 $a QH440 $b .D68 2018 082 04 $a 576.5072 $2 23 100 1 $a Doudna, Jennifer A., $e author. 245 12 $a A crack in creation : $b gene editing and the unthinkable power to control evolution / $c Jennifer A. Doudna, Samuel H. Sternberg. 250 $a First Mariner books edition. 264 1 $a Boston ; $b Mariner, $c 2018. 300 $a xx, 281 pages : $b illustrations ; $c 21 cm 504 $a Includes bibliographical references (pages 250-269) and index. 505 0 $a Prologue: the wave -- Part I. The tool -- The quest for a cure -- A new defense -- Cracking the code -- Command and control -- Part II. The task -- The CRISPR menagerie -- To heal the sick -- The reckoning -- What lies ahead -- Epilogue: the beginning. 520 $a Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences - to say nothing of the implications of intentionally mutating embryos to create "better" humans. Writing with fellow researcher Sam Sternberg, Doudna shares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life. 520 $a Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions. 650 0 $a CRISPR (Genetics) 650 0 $a Gene editing. 650 0 $a Genetic engineering $x History. 650 0 $a Genetics $x History. $x History. 650 0 $a Genetic code. 650 2 $a Gene Editing 650 2 $a Genetic Code 650 6 $a EÌdition geÌnique. 650 6 $a Code geÌneÌtique. 650 7 $a Science. $2 eflch 650 7 $a CRISPR (Genetics) $2 fast $0 (OCoLC)fst02000514 650 7 $a Gene editing. $2 fast $0 (OCoLC)fst02000662 650 7 $a Genetic code. $2 fast $0 (OCoLC)fst00939998 650 7 $a Genetic engineering. $2 fast $0 (OCoLC)fst00940027 650 7 $a Genetics $x Research. $2 fast $0 (OCoLC)fst00940133 650 7 $a Science. $2 ukslc 655 7 $a History. $2 fast $0 (OCoLC)fst01411628 700 1 $a Sternberg, Samuel H., $e author. 941 $a 2 952 $l OZAX845 $d 20240525041633.0 952 $l OVUX522 $d 20231117030148.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=66CF092EDB2811ECA7049CC04CECA4DB 994 $a 92 $b IOOInitiate Another SILO Locator Search