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06940aam a2200517Ii 4500 001 14443752E55411E7AFB0C42A97128E48 003 SILO 005 20171220010225 008 160613t20162016sz a b 101 0 eng d 010 $a 2016950723 020 $a 3319420429 020 $a 9783319420424 035 $a (OCoLC)951643039 040 $a YDXCP $b eng $e rda $c YDXCP $d BTCTA $d OCLCQ $d IAV $d OCLCO $d OCLCA $d YDX $d OCLCO $d SUC $d OCLCA $d CASUM $d OCLCO $d OCLCF $d NUI $d UtOrBLW $d SILO 050 4 $a QP551 $b .C69 2015 111 2 $a CNAPS (Conference) $n (9th : $d 2015 : $c Berlin, Germany) $0 http://id.loc.gov/authorities/names/nb2016025345 245 10 $a Circulating nucleic acids in serum and plasma : $b CNAPS IX / $c Peter B. Gahan, Michael Fleischhacker, Bernd Schmidt, editors. 246 30 $a CNAPS IX 264 1 $a Switzerland : $b Springer, $c [2016] 300 $a xxii, 220 pages : $b illustrations (some color) ; $c 27 cm. 490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v volume 924 504 $a Includes bibliographical references and index. 505 0 $a Part 1. Nucleic acides in oncology: prognosis, treatments screening and metastases. Circulating cell-free miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer -- Cell-free miRNA-141 and miRNA-205 as prostate cancer biomarkers -- Clinical utility of circulating tumor dna for molecular assessment and precision medicine in pancreatic cancer -- An enquiry concerning the characteristics of cell-free DNA released by cultured cancer cells -- Detection of p53 mutations in circulating DNA of transplanted hepatocellular carcinoma patients as a biomarker of tumor recurrence -- Unbiased detection of somatic copy number aberrations in cfDNA of lung cancer cases and high-risk controls with low coverage whole genome sequencing -- Liquid profiling in lung cancer - quantification of extracellular miRNAs in bronchial lavage -- Screening of KRAS mutation in pre- and post-surgery serum of patients suffering from colon cancer by COLD-PCR HRM -- Non-dividing cell virtosomes affect in vitro and in vivo tumour cell replication -- Features of circulating DNA fragmentation in blood of healthy females and breast cancer patients -- Liquid profiling of circulating nucleic acids as a novel tool for the management of cancer patients -- part 2. CNAPS in foetal medicine. Characterization of Human Pregnancy Specific Glycoprotein (PSG) gene copy number variations in pre-eclampsia patients -- Non-invasive prenatal diagnosis of feto-maternal platelet incompatibility by cold high resolution melting analysis -- Implementing Non-Invasive Prenatal Diagnosis (NIPD) in a National Health Service Laboratory; From Dominant to Recessive Disorders -- part 3. Biology of CNAPS. Comparative analysis of harmful physical factors effect on the cell genome -- Heterochromatic tandem repeats in the extracellular DNA -- A historical and evolutionary perspective on circulating nucleic acids and extracellular vesicles: circulating nucleic acids as homeostatic genetic entities -- Comparison of MicroRNA content in plasma and urine indicates the existence of a transrenal passage of selected MicroRNAs -- A quantitative assessment of cell-free DNA utilizing several housekeeping genes: measurements from four different cell lines -- Oligodeoxynucleotide analogues of circulating DNA inhibit dsRNA-induced immune response at the early stages of signal transduction cascade in a cell type-dependent manner -- GC-Rich DNA Fragments and oxidized cell-free DNA have different effects on NF-kB and NRF2 signaling in MSC -- Evaluation of the state of transplanted liver health by monitoring of organ-specific genomic marker in circulating DNA from receptor -- Vesicular and extra-vesicular RNAs of human blood plasma -- Artificial analogues of circulating box C/D rnas induce strong innate immune response and microRNA activation in human adenocarcinoma cells -- Multiple ways of cfDNA reception and following ROS production in endothelial cells -- Protein content of circulating nucleoprotein complexes -- part 4. Methodology. Digital PCR of genomic rearrangements for monitoring circulating tumour DNA -- mFast-SeqS as a monitoring and pre-screening tool for tumor-specific aneuploidy in plasma DNA -- Methodological variables in the analysis of cell-free DNA -- Novel technology for enrichment of biomolecules from cell-free body fluids and subsequent DNA sizing -- A rapid and sensitive method for detection of the T790M mutation of EGFR in plasma DNA -- Evaluation of different blood collection tubes and blood storage conditions for the preservation and stability of cell-free circulating DNA for the analysis of the methylated Msept9 colorectal cancer screening marker -- Purification of circulating cell-free DNA from plasma and urine using the automated large-volume extraction on the QIAsymphony SP Instrument -- Detection and quantification of KIT mutations in ctDNA by plasma Safe-SeqS -- part 5. Ethics. Lost in translation? ethical challenges of implementing a new diagnostic procedure -- Part 6. Round-table. Academia meets industry -- Index. 650 0 $a Nucleic acids $x Metabolism $v Congresses. 650 0 $a Blood $x Analysis $v Congresses. 650 12 $a Nucleic Acids $x analysis. $0 https://id.nlm.nih.gov/mesh/D009696Q000032 $0 https://id.nlm.nih.gov/mesh/D009696Q000032 650 22 $a Biomarkers, Tumor $x blood. $0 https://id.nlm.nih.gov/mesh/D014408Q000097 $0 https://id.nlm.nih.gov/mesh/D014408Q000097 650 22 $a Nucleic Acids $x blood. $0 https://id.nlm.nih.gov/mesh/D009696Q000097 $0 https://id.nlm.nih.gov/mesh/D009696Q000097 650 22 $a Prenatal Diagnosis $x methods. $0 https://id.nlm.nih.gov/mesh/D011296Q000379 $0 https://id.nlm.nih.gov/mesh/D011296Q000379 650 02 $a Female. $0 https://id.nlm.nih.gov/mesh/D005260 $0 https://id.nlm.nih.gov/mesh/D005260 650 02 $a Pregnancy. $0 https://id.nlm.nih.gov/mesh/D011247 $0 https://id.nlm.nih.gov/mesh/D011247 651 4 $a Berlin (Germany) 650 7 $a Blood $x Analysis. $2 fast $0 (OCoLC)fst00834552 650 7 $a Nucleic acids $x Metabolism. $2 fast $0 (OCoLC)fst01041076 648 4 $a 2015-09-10 $x 2015-09-12 655 4 $a Congresses. 655 4 $a Fulltext. 655 4 $a Internet Resources. 655 7 $a Conference papers and proceedings. $2 fast $0 http://id.worldcat.org/fast/1423772 $0 http://id.worldcat.org/fast/1423772 700 1 $a Gahan, Peter B., $e editor. $0 http://id.loc.gov/authorities/names/n84018019 700 1 $a Fleischhacker, Michael $c (Cancer researcher), $e editor. $0 http://id.loc.gov/authorities/names/no2017010240 700 1 $a Schmidt, Bernd $c (Cancer researcher), $e editor. $0 http://id.loc.gov/authorities/names/no2017010247 830 0 $a Advances in experimental medicine and biology ; $v v. 924. $x 0065-2598 $0 http://id.loc.gov/authorities/names/n42001229 941 $a 1 952 $l OVUX522 $d 20171220022633.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=14443752E55411E7AFB0C42A97128E48Initiate Another SILO Locator Search