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02595cam a22004454a 4500 001 3AA6B4A22B0D11DE82774608A8D7520A 003 SILO 005 20220831010537 008 060606s2006 gw a b 001 0 eng 020 $a 9783527314867 (alk. paper) 020 $a 3527314865 (alk. paper) 040 $a DNLM $c NLM $d SILO $d UKM $d BAKER $d YDXCP $d VAM $d CGC $d VRC $d NLGGC $d IXA $d TVG $d IWO $d SILO 042 $a pcc 072 7 $a RC $2 lcco 082 04 $a 616.994042 $2 22 084 $a 44.81 $2 bcl 100 1 $a Kiaris, Hippokratis. 245 1 $a Understanding carcinogenesis : $b an introduction to the molecular basis of cancer / $c Hippokratis Kiaris. 260 $a Weinheim : $b Wiley-VCH, $c c2006. 300 $a x, 177 p. : $b ill. $c 25 cm. 504 $a Includes bibliographical references and index. 505 0 $a Some introductory concepts in tumor biology: clonal evolution and autonomy versus non-autonomy of cancer cells -- The cell's life and death: cell cycle, senescence and apoptosis -- Oncogenes -- Tumor-suppressor genes -- Genomic instability -- A twist in the (genetic) tail: cancer epigenetics -- Nonautonomous interactions in carcinogenesis: role of the tumor stroma -- Telomerase and cellular immortality -- tumor angiogenesis -- Metastasis -- Tissue context as a determinant of the tumor-suppressive or oncogenic function of certain genes -- Cancer stem cells -- Determination of therapeutic efficacy-pharmacogenomics -- Certain chemicals induce cancer: chemical carcinogenesis -- Hormones and cancer -- Viral oncogenesis -- Cooperation of multiple biological processes is needed for the development of fully fledged malignancy -- Carcinogenesis in vivo: animal models and basic approaches to generate genetically modified animals -- Multistage carcinogenesis in humans: molecular epidemiology and the colon cancer model -- Epilogue. 650 04 $a Neoplastik huÌcre farklılaşması $x Genetik. 650 04 $a MolekuÌler biyoloji. 650 04 $a TuÌmoÌrler $x Genetik. 650 04 $a Kanser oluşumu $x MolekuÌler açıdan. 650 12 $a Cell Transformation, Neoplastic $x genetics. 650 22 $a Molecular Biology. 650 22 $a Neoplasms $x genetics. 650 0 $a Carcinogenesis $x Molecular aspects. 650 0 $a Cancer $x Genetic aspects. 650 0 $a Mutation (Biology) 650 17 $a Carcinogenese. $2 gtt 650 17 $a Moleculen. $2 gtt 650 17 $a Kanker. $2 gtt 941 $a 2 952 $l OVUX522 $d 20171228015420.0 952 $l USUX851 $d 20160823071312.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=3AA6B4A22B0D11DE82774608A8D7520A 994 $a 02 $b IWOInitiate Another SILO Locator Search