497 records matched your query
03161aam a2200337 i 4500 001 BE3F604AAC9F11EBAF53C5C920ECA4DB 003 SILO 005 20210504011201 008 200407s2020 ncua b 001 0 eng 010 $a 2020005712 020 $a 1476678618 020 $a 9781476678610 (softcover) 040 $a DLC $b eng $c DLC $e rda $d DLC $d SILO 042 $a pcc 050 00 $a RC523 $b .M6648 2020 082 00 $a 616.8/311 $2 23 100 1 $a Moore, Elaine A., $d 1948- $e author. 245 10 $a Alzheimer's disease and infectious causes : $b the theory and evidence / $c Elaine A. Moore. 264 1 $a Jefferson, North Carolina : $b McFarland & Company, Inc., Publishers, $c [2020] 300 $a vii, 224 pages : $b illustrations ; $c 23 cm 490 0 $a McFarland health topics 504 $a Includes bibliographical references (pages 203-213) and index. 505 0 $a One-The Mystery of the Mind and Consciousness -- Two-Infection as a Primary Cause of Alzheimer's Disease -- Three-Microorganisms and the Microbiome -- Four-The Immune System, Neurodegeneration -- and the Blood-Brain Barrier -- Five-Alzheimer's Disease: Its Stages and Pathology -- Six-Herpes Viruses in Alzheimer's Disease -- Seven-Other Associated Viruses and the Prion Connection -- in Alzheimer's Disease -- Eight-Bacterial Infections Implicated in Alzheimer's Disease -- Nine-Fungal and Protozoan Infections in Alzheimer's Disease -- Ten-Alzheimer's Disease Risk Factors -- Eleven-Genetic Influences in Alzheimer's Disease -- Twelve-Risk Reduction and Therapies in Alzheimer's Disease. 520 $a "With the recent discovery that amyloid beta protein, the cause of plaques in Alzheimer's disease, is an antimicrobial peptide produced in response to infection, many researchers are focusing on the role infection plays in the development of Alzheimer's disease. Brain studies have also identified a number of different viruses, bacteria, fungi, and protozoa in the postmortem brain specimens of Alzheimer's patients. Infection (particularly chronic, latent and persistent infections) causes an immune response that leads to inflammation and brain cell degeneration, which are characteristic features of Alzheimer's disease. Sources of infection in Alzheimer's disease vary from childhood infections to gut microbes that find their way into the brain as a result of aging, leaky gut syndrome, and increased permeability of the blood brain barrier. Studies and ongoing clinical trials show that treatment of viral and bacterial infections, as well as restoring a healthy balance to the gut microbiome, can reduce disease risk and improve symptoms in patients with Alzheimer's disease. This book serves as an introduction to the human microbiome and the role that infection plays in the development of Alzheimer's disease."-Provided by publisher"-- $c Provided by publisher. 650 0 $a Alzheimer's disease $x Etiology. 650 0 $a Alzheimer's disease $x Risk factors. 650 0 $a Infection $x Complications. 941 $a 2 952 $l PNAX964 $d 20220209011133.0 952 $l GBPF771 $d 20210504013833.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=BE3F604AAC9F11EBAF53C5C920ECA4DBInitiate Another SILO Locator Search