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03206aam a2200397 i 4500 001 0C37DB20621111E7BC2B04C5DAD10320 003 SILO 005 20170706010219 008 170128t20172017nyu b 001 0 eng c 010 $a 2017003468 020 $a 1479876992 020 $a 9781479876990 020 $a 1479836982 020 $a 9781479836987 035 $a (OCoLC)961160724 040 $a PUL $b eng $e rda $c PUL $d BTCTA $d YDX $d BDX $d KSU $d DLC $d SILO 042 $a pcc 050 00 $a RG136 G67 2017 100 1 $a Green, William, $d 1950- $e author. 245 10 $a Contraceptive risk : $b the FDA, Depo-Provera, and the politics of experimental medicine / $c William Green. 264 1 $a New York : $b New York University Press, $c [2017] 300 $a xiii, 322 pages ; $c 23 cm. 490 1 $a Biopolitics : medicine, technoscience, and health in the 21st century 504 $a Includes bibliographical references (pages 239-303) and index. 505 0 $a Introduction : the odyssey of Depo-Provera -- The Grady Hospital study : the corruption of contraceptive research -- The twenty-five-year FDA approval controversy : cancer and the politics of acceptable risk -- Contraceptive chaos : unapproved use and Upjohn v. MacMurdo -- Marketing approval and litigation : osteoporosis and the realities of medical risk -- Chemical castration : the John Hopkins Clinic and People v. Gauntlett -- Conclusions : contraceptive drug risk failure, human dignity, and a duty to act. 520 $a "Depo-Provera is known as an injectable hormonal birth control method, but few are familiar with its dark and complicated history. Depo-Provera was tested on women since the mid-1960s without their informed consent until it was FDA-approved in 1992, but never FDA-approved as chemical castration for male sex offenders. Contraceptive risk is William Green's landmark study of Depo-Provera. Based on a fascinating combination of archival materials and interviews, the book is framed as three interconnected stories told by Judith Weisz, who chaired the FDA's Public Board of Inquiry on Depo-Provera, a scientific court; by Anne MacMurdo who brought a products liability suit against Upjohn, the drug's manufacturer, for the deleterious side effects she suffered from the drug's use; and by Roger Gauntlett, an Upjohn heir who, when he was convicted of sexual assault, refused to take a dose of his family's own medicine as a probation condition. Together these three stories of Depo-Provera's convoluted fifty year odyssey call for a paradigm shift in pharmaceutical drug development. Contraceptive risk is a thoroughly researched and engrossing approach to the scientific, political and institutional forces involved in health law and policy, as well as the multifaceted politics of measuring risk"--Back cover. 650 0 $a Contraception. 650 0 $a Women $x Health risk assessment. 650 0 $a Contraceptives $x Safety measures. 830 0 $a Biopolitics (New York, N.Y.) 941 $a 3 952 $l OVUX522 $d 20191210030013.0 952 $l UQAX771 $d 20180426011454.0 952 $l USUX851 $d 20171003032020.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=0C37DB20621111E7BC2B04C5DAD10320 994 $a C0 $b IWAInitiate Another SILO Locator Search