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03804aam a2200433 i 4500 001 DB6B08E0101A11EA8DA14E4D97128E48 003 SILO 005 20191126010151 008 171026s2018 maua b 001 0 eng 010 $a 2017047175 020 $a 0262038056 020 $a 9780262038058 035 $a (OCoLC)1004065905 040 $a DLC $b eng $e rda $c DLC $d OCLCF $d OCLCO $d OCLCQ $d TOH $d MYG $d OBE $d YDX $d OCLCO $d UPM $d YUS $d WTU $d OCLCO $d YOU $d OCLCO $d UIU $d NLE $d OCLCO $d CUY $d OCLCO $d NLM $d OCLCO $d UtOrBLW $d SILO 042 $a pcc 050 00 $a QP383.7 $b .L46 2018 060 00 $a 2018 G-796 060 10 $a WL 312 082 00 $a 573.4/59 $2 23 100 1 $a Leng, G. $q (Gareth), $e author. $0 http://id.loc.gov/authorities/names/n83056686 245 14 $a The heart of the brain : $b the hypothalamus and its hormones / $c Gareth Leng. 264 1 $a Cambridge, MA : $b The MIT Press, $c [2018] 300 $a x, 265 pages : $b illustrations ; $c 24 cm 520 $a "This book is about the neuroendocrine brain - about the hypothalamus, the seat of our passions, and about the control that this small structure exerts on our physiology and behavior. The hypothalamus contains a vast diversity of neuronal types, and these signal not only though conventional messengers but by a wide range of other signals, many of which act as hormones within the brain. Behaviors important to who we are - love and hate, how much we eat and what we eat, how we respond to threat and to stress - are governed by the hypothalamus, and not by the map of how the neurons are connected, but by where the receptors for these peptide signals are found. Neurotransmitter signals are ephemeral and confined by anatomical connectivity, but the peptide signals that hypothalamic neurons generate are potent, wide reaching and long-lasting, and they affect not just neuronal excitability but also the genes that neurons express. Remarkably, different peptides when injected into the brain induce coherent, meaningful behaviors - some trigger eating, others induce a longing for salt, or initiate maternal behavior or aggression or sleep. This book describes the frontiers of current research into the hypothalamus, and does so in a way that makes it accessible to readers with no specialized knowledge."-- $c Provided by publisher. 504 $a Includes bibliographical references and index. 505 0 $a Preface -- Prelude -- The European Brain -- The Classical Neuron -- Enlightenment -- Far from the Madding Crowd -- Pulsatile Secretion -- Dendritic Secretion and Priming -- The GnRH Neuron -- Kisspeptin -- The Bistable Neuron -- Vasopressin -- Numbers -- Whispered Secrets and Public Announcements -- Plasticity -- Rhythms -- Obesity -- The Empty Medicine Cabinet -- Appetite -- The Sweet Hormone -- The Hybrid Neuron -- Behavior -- The Evolved Brain -- Redundancy and Degeneracy -- The Tangled Web. 650 0 $a Hypothalamus $v Popular works. 650 0 $a Hypothalamic hormones $v Popular works. 650 7 $a Hypothalamic hormones. $2 fast $0 (OCoLC)fst00966071 650 7 $a Hypothalamus. $2 fast $0 (OCoLC)fst00966079 650 7 $a SCIENCE / Life Sciences / Anatomy & Physiology. $2 bisacsh 650 12 $a Hypothalamus $x physiology. $0 https://id.nlm.nih.gov/mesh/D007031Q000502 650 22 $a Hypothalamic Hormones $x physiology. $0 https://id.nlm.nih.gov/mesh/D007028Q000502 650 22 $a Neurons $x physiology. $0 https://id.nlm.nih.gov/mesh/D009474Q000502 655 7 $a Popular works. $2 fast $0 http://id.worldcat.org/fast/1423846 $0 http://id.worldcat.org/fast/1423846 776 08 $i Electronic version: $a Leng, G. (Gareth). $t Heart of the brain. $d Cambridge, MA : The MIT Press, [2018] $z 9780262346993 $w (OCoLC)1043830951 941 $a 1 952 $l OVUX522 $d 20191217023428.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=DB6B08E0101A11EA8DA14E4D97128E48Initiate Another SILO Locator Search