Future directions in glycosciences / Historical background and overview / Gerald W. Hart and Ajit Varki. Monosaccharide diversity / Peter H. Seeberger -- Oligosaccharides and polysaccharides / James H. Prestegard, Jian Liu, and Göran Widmalm -- Cellular organization of glycosylation / Karen J. Colley, Ajit Varki, and Taroh Kinoshita -- Glycosylation precursors / Hudson H. Freeze, Gerald W. Hart, and Ronald L. Schnaar -- Glycosyltransferases and glycan-processing enzymes / James M. Rini and Jeffrey D. Esko -- Biological functions of glycans / Ajit Varki and Pascal Gagneux -- A genomic view of glycobiology / Bernard Henrissat, Avadesha Surolia, and Pamela Stanley -- Structure and biosynethis. N-glycans / Pamela Stanley, Naoyuki Taniguchi, and Markus Aebi -- O-GalNAc glycans / Inka Brockhausen and Pamela Stanley -- Glycosphingolipids / Ronald L. Schnaar and Taroh Kinoshita -- Glycosylphosphatidylinositol anchors / Michael A.J. Ferguson, Gerald W. Hart, and Taroh Kinoshita -- Other classes of eukaryotic glycans / Robert S. Haltiwanger, Lance Wells, Hudson H. Freeze, and Pamela Stanley -- Structures common to different glycans / Pamela Stanley and Richard D. Cummings -- Sialic acids and other nonulosonic acids / Ajit Varki, Ronald L. Schnaar, and Roland Schauer -- Hyaluronan / Vincent Hascall and Jeffrey D. Esko -- Proteoglycans and sulfated glycosaminoglycans / Ulf Lindahl, John Couchman, Koji Kimata, and Jeffrey D. Esko -- Nucleocytoplasmic glycosylation / Christopher M. West and Gerald W. Hunt -- The O-GlcNAc modification / Natasha Zachara, Yoshihiro Akimoto, and Gerald W. Hart -- Glycans in evolution and development. Evolution of glycan diversity / Pascal Gagneux, Markus Aebi, and Ajit Varki -- Eubacteria / Chris Whitfield, Christine M. Szymanski, and Markus Aebi -- Archaea / Sonja Albers, Jerry Eichler, and Markus Aebi -- Fungi / Tamara L. Doering, Richard D. Cummings, and Markus Aebi -- Viridiplantae and algae / Malcolm A. O'Neill, Alan G. Darvill, Marilynn E. Etzler, Debra Mohnen, and Serge Perez -- Nematoda / Iain B.H. Wilson, Richard D. Cummings, and Markus Aebi -- Arthropoda / Michael Tiemeyer, Hiroshi Nakato, and Jeffrey D. Esko -- Deuterostomes / Michael Pierce and Pamela Stanley -- Glycan-binding proteins. Discovery and classification of glycan-binding proteins / Maureen E. Taylor, Kurt Drickamer, Ronald L. Schnaar, Marilynn E. Etzler, and Ajit Varki -- Principles of glycan recognition / Richard D. Cummings, Ronald L. Schnaar, Jeffrey D. Esko, Kurt Drickamer, and Maureen E. Taylor -- Structural biology of glycan recognition / Anne Imberty and James H. Prestegard -- R-type lectins / Richard D. Cummings and Ronald L. Schnaar -- L-type lectins / Richard D. Cummings, Marilynn E. Etzler, and Avadhesha Surolia -- P-type lectins / Ajit Varki and Stuart Kornfeld -- C-type lectins / Richard Cummings and Rodger P. McEver -- I-type lectins / Ajit Varki, Ronald L. Schnaar, and Paul R. Crocker -- Galectins / Richard D. Cummings, Fu-Tong Liu, and Gerardo R. Vasta -- Microbial lectins: hemagglutinins, adhesins, and toxins / Victor Nizet, Ajit Varki, and Markus Aebi -- Proteins that bind sulfated glycosaminoglycans / Jeffrey D. Esko, James H. Prestegard, and Robert J. Linhardt -- Glycans in physiology and disease. Glycans in glycoprotein quality control / Armando Parodi, Richard D. Cummings, and Markus Aebi -- Free glycans as signaling molecules / Malcolm A. O'Neill, Alan G. Darvill, Marilynn E. Etzler, and Jeffrey D. Esko -- Glycans in systemic physiology / Hudson H. Freeze, Linda Baum, and Ajit Varki -- Bacterial and viral infections / Christine M. Szymanski, Ronald L. Schnaar, and Markus Aebi -- Parasitic infections / Richard D. Cummings and Irma van Die -- Genetic disorders of glycan degradation / Hudson H. Freeze, Taroh Kinoshita, and Ronald L. Schnaar -- Genetic disorders of glycosylation / Hudson H. Freeze, Harry Schachter, and Taroh Kinoshita -- Glycans in acquired human diseases / Hudson H. Freeze, Taroh Kinoshita, and Ajit Varka -- Glycosylation changes in cancer / Ajit Varki, Reiji Kannagi, Bryan Toole, and Pamela Stanley -- Methods and applications. Glycan-recognizing probes as tools / Richard D. Cummings, Alan G. Darvill, Marilynn E. Etzler, and Michael G. Hahn -- Glycosylation mutants of cultured mammalian cells / Jeffrey D. Esko and Pamela Stanley -- Structural analysis of glycans / Barbara Mulloy, Anne Dell, Pamela Stanley, and James H. Prestegard -- Glycomics and glycoproteomics / Pauline Rudd, Niclas G. Karlsson, Kay-Hooi Khoo, and Nicolle H. Packer -- Glycoinformatics / Matthew P. Campbell, Kiyoko F. Aoki-Kinoshita, Frederique Lisacek, William S. York, and Nicolle H. Packer -- Chemical synthesis of glycans and glycoconjugates / Peter H. Seeberger and Hermen S. Overkleeft -- Chemoenzymatic synthesis of glycans and glycoconjugates / Hermen S. Overkleeft and Peter H. Seeberger -- Chemical tools for inhibiting glycosylation / Jeffrey D. Esko, Carolyn Bertozzi, and Ronald L. Schnaar -- Glycosylation engineering / Henrik Clausen, Hans H. Wandall, Catharina Steentoft, Pamela Stanley, and Ronald L. Schnaar -- Glycans in biotechnology and the pharmaceutical industry / Peter H. Seeberger and Richard D. Cummings -- Glycans in nanotechnology / Soledad Penadés, Benjamin G. Davis, and Peter H. Seeberger -- Glycans in bioenergy and materials science / Malcolm A. O'Neill, Robert J. Moon, William S. York, and Alan G. Darvill -- Future directions in glycosciences / Gerald W. Hart and Ajit Varki.
Summary:
"Defined in the broadest sense, Glycobiology is the study of the structure, biosynthesis, biology, and evolution of saccharides (sugar chains or glycans) that are widely distributed in nature in all living life forms. Glycobiology is now one of the more rapidly growing fields in the natural sciences, with broad relevance to many areas of basic research, biomedicine, and biotechnology. The field includes the chemistry of carbohydrates, the enzymology of glycan formation and degradation, the recognition of glycans by specific proteins, roles of glycans in complex biological systems, and their analysis or manipulation by various techniques. The third edition of this primary textbook in the field continues in the prior tradition, seeking to provide basic overview of Glycobiology, directed towards the advanced undergraduate or the beginning graduate-level student of molecular and cellular biology and biomedicine. "--Amazon.com.
This resource is supported by the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act as administered by State Library of Iowa.