Bacterial evasion of the host immune system / edited by Pedro Escoll ; Institut Pasteur Biologie des Bactéries Intracellulaires ; and Centre National de la Recherche Scientifique (CNRS) UMR 3525, Paris, France.
Publisher:
Caister Academic Press
Copyright Date:
2017
Description:
vi, 224 pages : illustrations (some color) ; 24 cm
Secretion systems used by bacteria to subvert host functions / Chiara Rapisarda and Rémi Fronzes -- Within-host envelope remodelling and its impact in bacerial pathogen recognition / M. Graciela Pucciarelli and Francisco García-del Portillo -- Subversion of macrophage functions by bacterial protein toxins and effectors / Muyang Wan, Yan Zhou and Yongqun Zhu -- Manipulation of autophagy by bacterial pathogens impacts host immunity / Tobias C. Kunz, Flávia Viana, Carmen Buchrieser and Pedro Escoll -- Inflammasome-dependent mechanisms involved in sensing and restriction of bacterial replication / Warrison A. Andrade and Dario S. Zamboni -- Molecular mechanisms used by Salmonella to evade the immune system / Joaquín Bernal-Bayard and Fancisco Ramos-Morales -- Immunie-evasion strategies of mycobacteria and their implications for the protective immune response / Alexandra G. Fraga, Ana Margarida Barbosa, Catarina M. Ferreira, João Fevereiro, Jorge Pedrosa and Egídio Torrado -- Role of cyclic di-GMP in the bacterial virulence and evasion of the plant immunity.
Summary:
Infectious diseases continue to be a major threat to human health with predictions that these will account for one of five deaths globally over the coming decades. The worrying rise in antibiotic resistance in bacterial pathogens only serves to exacerbate this situation. Many pathogenic bacteria have evolved an array of sophisticated mechanisms to evade the host's immune response: some even exploit host functions to avoid detection by immune cells. Understanding the mechanisms of this subversion is critical for the understanding of bacterial pathogenesis and could be used for the development of novel antibacterial strategies. In this volume expert authors critically review the most important current research in this exciting field. From back cover.
This resource is supported by the Institute of Museum and Library Services under the provisions of the Library Services and Technology Act as administered by State Library of Iowa.