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02900aam a2200397 a 4500 001 D4819E08D87911E1929E61EA6AFF544E 003 SILO 005 20120728010119 007 cr cn||||||||| 008 110610s2011 dcua b 100 0 eng 010 $a 2011284048 020 $a 0309211042 020 $a 9780309211048 035 $a (OCoLC)730412357 040 $a NLM $b eng $c NLM $d SILO $d DLC $d NRZ $d UPM $d YDXCP $d UKMGB $d CDX $d OCLCQ $d SILO 042 $a pcc 245 0 $a Generating evidence for genomic diagnostic test development : $b workshop summary / $c Theresa Wizemann and Adam C. Berger, rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies. 260 $a Washington, D.C. : $b National Academies Press, $c c2011. 300 $a xx, 85 p. : $b ill. ; $c 23 cm. 504 $a Includes bibliographical references (p. 63-66). 520 $a "Ten years after the sequencing of the human genome, scientists have developed genetic tests that can predict a person's response to certain drugs, estimate the risk of developing Alzheimer's disease, and make other predictions based on known links between genes and diseases. However, genetic tests have yet to become a routine part of medical care, in part because there is not enough evidence to show they help improve patients' health. The Institute of Medicine (IOM) held a workshop to explore how researchers can gather better evidence more efficiently on the clinical utility of genetic tests. Generating Evidence for Genomic Diagnostic Test Development compares the evidence that is required for decisions regarding clearance, use, and reimbursement, to the evidence that is currently generated. The report also addresses innovative and efficient ways to generate high-quality evidence, as well as barriers to generating this evidence. Generating Evidence for Genomic Diagnostic Test Development contains information that will be of great value to regulators and policymakers, payers, health-care providers, researchers, funders, and evidence-based review groups."--Publisher's description. 530 $a Also issued online. 650 0 $a Genomics $v Congresses. 650 0 $a Human chromosome abnormalities $x Diagnosis $v Congresses. 650 0 $a Genetic counseling $v Congresses. 650 0 $a Genetic disorders $x Diagnosis $v Congresses. 650 12 $a Genomics $v Congresses. 650 22 $a Chromosome Aberrations $v Congresses. 650 22 $a Genetic Counseling $v Congresses. 650 22 $a Genetic Diseases, Inborn $x diagnosis $v Congresses. 700 1 $a Wizemann, Theresa M. 700 1 $a Berger, Adam C. 710 2 $a Institute of Medicine (U.S.). $b Roundtable on Translating Genomic-Based Research for Health. 941 $a 1 952 $l USUX851 $d 20160826054452.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=D4819E08D87911E1929E61EA6AFF544EInitiate Another SILO Locator Search