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02809aam a2200313Ii 4500 001 03CAAA26621111E7BC2B04C5DAD10320 003 SILO 005 20170706010219 008 170502t20172017dcua b 000 0 eng d 020 $a 0309453291 020 $a 9780309453295 035 $a (OCoLC)985121178 040 $a TKN $b eng $e rda $c TKN $d OCLCO $d SOI $d OCLCO $d NRC $d OCLCO $d IWA $d SILO 050 4 $a RB155.65 N38x 2017 110 2 $a National Academies of Sciences, Engineering, and Medicine (U.S.). $b Committee on the Evidence Base for Genetic Testing, $e author. 245 13 $a An evidence framework for genetic testing / $c Committee on the Evidence Base for Genetic Testing, Board on the Health of Select Populations, Board on Health Care Services, Health and Medicine Division, a report of the National Academies of Sciences, Engineering, Medicine. 264 1 $a Washington, DC : $b the National Academies Press, $c [2017] 300 $a xii, 136 pages : $b illustrations ; $c 28 cm 504 $a Includes bibliographical references (pages 111-130). 505 0 $a Introduction -- Genetic testing -- Genetic test assessment -- Evidence -- An evidence framework for genetic testing -- Appendix A. Understanding genetic variance and phenotype expression -- Appendix B: the GETT checklist -- Appendix C:. Using evidence to inform clinical and policy decision -- References -- Glossary. 520 1 $a "Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care"--Publisher's description. 650 0 $a Genetic screening. 650 0 $a Gene expression $x Testing. 650 0 $a Medical genetics. 650 0 $a Human chromosome abnormalities $x Diagnosis. 941 $a 2 952 $l OZAX845 $d 20240525041619.0 952 $l USUX851 $d 20170802025006.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=03CAAA26621111E7BC2B04C5DAD10320Initiate Another SILO Locator Search