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03116aam a2200457 i 4500 001 5699BD8A237811E4AF5831D6DAD10320 003 SILO 005 20140814010041 008 130325s2013 njua b 001 0 eng 010 $a 2013011850 020 $a 069114978X 020 $a 9780691149783 040 $a DLC $b eng $e rda $c DLC $d IG# $d OCLCO $d YDXCP $d BTCTA $d BDX $d UKMGB $d PUL $d VET $d CDX $d TWC $d OCLCF $d ZCU $d NLM $d WUM $d CUD $d VP@ $d NLGGC $d SILO 042 $a pcc 050 00 $a RC523 $b .L63 2013 100 1 $a Lock, Margaret M. 245 14 $a The Alzheimer conundrum : $b entanglements of dementia and aging / $c Margaret Lock. 264 1 $a Princeton, New Jersey : $b Princeton University Press, $c [2013] 300 $a x, 310 pages : $b illustrations ; $c 24 cm 504 $a Includes bibliographical references (pages [277]-299 and index (pages [301]-310). 505 0 $a Making and remaking Alzheimer disease -- Striving to standardize Alzheimer disease -- Paths to Alzheimer prevention -- Embodied risk made visible -- Alzheimer genes: biomarkers of prediction and prevention -- Genome-wide association studies: back to the future -- Living with embodied omens -- Chance untamed and the return of fate -- Transcending entrenched tensions -- Portraits from the mind. 520 $a Based on a careful study of the history of Alzheimer's disease and extensive in-depth interviews with clinicians, scientists, epidemiologists, geneticists, and others, Margaret Lock highlights the limitations and the dissent implicated in this approach. She stresses that one major difficulty is the well-documented absence of behavioral signs of Alzheimer's disease in a significant proportion of elderly individuals, even when Alzheimer neuropathology is present in their brains. This incongruity makes it difficult to distinguish between what counts as normal versus pathological and, further, makes it evident that social and biological processes contribute inseparably to aging. Lock argues that basic research must continue, but it should be complemented by a realistic public health approach available everywhere that will be more effective and more humane than one focused almost exclusively on an increasingly frenzied search for a cure. 650 0 $a Alzheimer's disease $x Age factors. 650 0 $a Older people $x Mental health. 650 0 $a Brain $x Molecular aspects. $x Molecular aspects. 650 7 $a Alzheimer's disease $x Age factors. $2 fast $0 (OCoLC)fst01750368 650 7 $a Brain $x Molecular aspects. $x Molecular aspects. $2 fast $0 (OCoLC)fst00837576 650 7 $a Older people $x Mental health. $2 fast $0 (OCoLC)fst01199117 650 12 $a Alzheimer Disease $x diagnosis. 650 22 $a Age Factors. 650 22 $a Aging $x physiology. 650 22 $a Alzheimer Disease $x epidemiology. 650 22 $a Brain $x physiology. 650 22 $a Risk Assessment. 941 $a 4 952 $l USUX851 $d 20160826082939.0 952 $l SOAX911 $d 20160506011341.0 952 $l PNAX964 $d 20141218011922.0 952 $l UQAX771 $d 20140814010253.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=5699BD8A237811E4AF5831D6DAD10320 994 $a C0 $b JIDInitiate Another SILO Locator Search