17 records matched your query
02948aam a2200409 i 4500 001 5FB76844992D11EC82317EFE47ECA4DB 003 SILO 005 20220301010056 008 201124s2021 paua b 001 0 eng 010 $a 2020052526 020 $a 0822946300 020 $a 9780822946304 035 $a (OCoLC)1145092126 040 $a DLC $b eng $e rda $c DLC $d OCLCO $d OCLCF $d UKMGB $d YDX $d OCLCO $d OCLCA $d IVV $d OCLCO $d SILO 042 $a pcc 050 00 $a QR360 $b .S26 2021 060 4 $a QW 11.1 082 00 $a 579.2 $2 23 100 1 $a Sankaran, Neeraja, $e author. 245 12 $a A tale of two viruses : $b parallels in the research trajectories of tumor and bacterial viruses / $c Neeraja Sankaran. 264 1 $a Pittsburgh Pa. : $b University of Pittsburgh Press, $c [2021] 300 $a xvi, 296 pages : $b illustrations ; $c 24 cm 504 $a Includes bibliographical references and index. 520 $a "In 1965, French microbiologist AndreÌ Lwoff was awarded the Nobel Prize in Physiology or Medicine for his work on lysogeny-one of the two types of viral life cycles-which resolved a contentious debate among scientists about the nature of viruses. A Tale of Two Viruses is the first study of medical virology to compare the history of two groups of medically important viruses-bacteriophages, which infect bacteria, and sarcoma agents, which cause cancer-and the importance of Lwoff's discovery to our modern understanding of what a virus is. Although these two groups of viruses may at first glance appear to have little in common, they share uniquely parallel histories. The lysogenic cycle, unlike the lytic, enables viruses to replicate in the host cell without destroying it and to remain dormant in a cell's genetic material indefinitely, or until induced by UV radiation. But until Lwoff's discovery of the mechanism of lysogeny, microbiologist FeÌlix d'Herelle and pathologist Peyton Rous, who themselves first discovered and argued for the viral identity of bacteriophages and certain types of cancer, respectively, faced opposition from contemporary researchers who would not accept their findings. By following the research trajectories of the two virus groups, Sankaran takes a novel approach to the history of the development of the field of medical virology, considering both the flux in scientific concepts over time and the broader scientific landscapes or styles that shaped those ideas and practices"-- $c Provided by publisher. 650 0 $a Viruses. 650 0 $a Bacteriophages. 650 0 $a Sarcoma. 650 2 $a Virology $x history 650 2 $a Bacteriophages 650 2 $a Sarcoma $x virology 650 7 $a Bacteriophages. $2 fast $0 (OCoLC)fst00825287 650 7 $a Sarcoma. $2 fast $0 (OCoLC)fst01105477 650 7 $a Viruses. $2 fast $0 (OCoLC)fst01167771 941 $a 1 952 $l UNUX074 $d 20220301010950.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=5FB76844992D11EC82317EFE47ECA4DB 994 $a Z0 $b NIUInitiate Another SILO Locator Search