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03428aam a2200385 a 4500 001 C9FD0DFE033A11E8972C924897128E48 003 SILO 005 20180127021036 008 060125t20052005nyua b 001 0 eng 020 $a 9781402037641 020 $a 1402037643 020 $a 9781402037634 020 $a 1402037635 035 $a (OCoLC)63394908 040 $a UKM $b eng $c UKM $d OHX $d BAKER $d DAY $d COU $d IaU $d UtOrBLW $d SILO 042 $a pcc 050 4 $a RC268.4 $b .G47 2005 245 00 $a Genome instability in cancer development / $c edited by Erich A. Nigg. 264 1 $a New York : $b Springer, $c [2005] 300 $a xv, 511 pages : $b illustrations (some color) ; $c 26 cm. 490 1 $a Advances in experimental medicine and biology ; $v v. 570 504 $a Includes bibliographical references and index. 505 0 $a The problem of genome instability. The multiplicity of mutations in human cancers / Ranga N. Venkatesan and Lawrence A. Loeb. Monitoring chromosome rearrangements / Michael R. Speicher -- DNA repair and mutagenesis. Nucleotide excision repair and its connection with cancer and ageing / Jaan-Olle Andressoo, Jan H.J. Hoeijmakers and Harm de Waard. DNA mismatch repair and colon cancer / Giancarlo Marra and Josef Jiricny. Base excision repair / Lisiane B. Meira, Nicholas E. Burgis and Leona D. Samson. Genomic instability in cancer development / Penny A. Jeggo. Translesion synthesis and error-prone polymerases / Catherine M. Green and Alan R. Lehmann -- Cell cycle progression and chromosome aberration. The INK4A/ARF network-cell cycle checkpoint or emergency brake? / Ana Gutierrez del Arroyo and Gordon Peters. DNA replication and genomic instability / Wenge Zhu, Tarek Abbas and Anindya Dutta. The dream of every chromosome: equal segregation for a healthy life of the host / Tomohiro Matsumoto and Mitsuhiro Yanagida. Telomere structural dynamics in genome integrity control and carcinogenesis / Roger A. Greenberg and K. Lenhard Rudolph. Gene amplification mechanisms / Michelle Debatisse and Bernard Malfoy. DNA methylation and cancer-associated genetic instability / Melanie Ehrlich. Deregulation of the centrosome cycle and the origin of chromosomal instability in cancer / Wilma L. Lingle, Kara Lukaswiewicz and Jeffrey L. Salisbury -- Genome integrity checkpoints. Mammalian DNA damage response pathway / Zhenkun Lou and Junjie Chen. ATM and cellular response to DNA damage / Martin F. Lavin ... [et al.] Mitotic checkpoint, aneuploidy and cancer / Tim J. Yen and Gary D. Kao. 650 0 $a Cancer $x Genetic aspects. $0 http://id.loc.gov/authorities/subjects/sh85019509 650 0 $a Genomics. $0 http://id.loc.gov/authorities/subjects/sh2002000809 650 12 $a Neoplasms $x genetics. $2 [MeSH] $0 https://id.nlm.nih.gov/mesh/D009369Q000235 650 12 $a Neoplasms $x etiology. $2 [MeSH] $0 https://id.nlm.nih.gov/mesh/D009369Q000209 650 22 $a Genomic Instability. $2 [MeSH] $0 https://id.nlm.nih.gov/mesh/D042822 650 22 $a Mutation. $2 [MeSH] $0 https://id.nlm.nih.gov/mesh/D009154 650 22 $a DNA Repair. $2 [MeSH] $0 https://id.nlm.nih.gov/mesh/D004260 700 1 $a Nigg, Erich A. $0 http://id.loc.gov/authorities/names/nb2004303253 830 0 $a Advances in experimental medicine and biology ; $v v. 570. $0 http://id.loc.gov/authorities/names/n42001229 941 $a 1 952 $l OVUX522 $d 20180127065834.0 956 $a http://locator.silo.lib.ia.us/search.cgi?index_0=id&term_0=C9FD0DFE033A11E8972C924897128E48Initiate Another SILO Locator Search